Compile Data Set for Download or QSAR
Found 1 of ic50 for monomerid = 544933
TargetEukaryotic translation initiation factor 4E-binding protein 1(Homo sapiens (Human))
eFFECTOR Therapeutics, Inc.

US Patent
LigandPNGBDBM544933(US11286268, Compound 419)
Show SMILES Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cnc(C)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1
Show InChI InChI=1S/C27H20ClN5O4S/c1-13-8-18(25-24(31-13)20(12-38-25)27(35)36)17-9-16(28)4-5-22(17)37-7-6-33-15(3)32-21-11-30-14(2)19(10-29)23(21)26(33)34/h4-5,8-9,11-12H,6-7H2,1-3H3,(H,35,36)
Affinity DataIC50: 1.08nMAssay Description:eIF4E protein was pre-incubated with EDA-m7GDP-ATTO-550 in FPB at 2xconcentrations for 5 minutes prior to the addition of compounds. Compounds (100x)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid