Compile Data Set for Download or QSAR
Found 1 of ic50 for monomerid = 545168
TargetEukaryotic translation initiation factor 4E-binding protein 1(Homo sapiens (Human))
eFFECTOR Therapeutics, Inc.

US Patent
LigandPNGBDBM545168(US11286268, Compound 654)
Show SMILES Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(cc(C#N)c3c2=O)-c2cccnc2)c2scc(C(O)=O)c2n1
Show InChI InChI=1S/C32H22ClN5O4S/c1-17-10-24(30-29(36-17)25(16-43-30)32(40)41)23-13-22(33)5-6-27(23)42-9-8-38-18(2)37-26-12-20(19-4-3-7-35-15-19)11-21(14-34)28(26)31(38)39/h3-7,10-13,15-16H,8-9H2,1-2H3,(H,40,41)
Affinity DataIC50: 3.12nMAssay Description:eIF4E protein was pre-incubated with EDA-m7GDP-ATTO-550 in FPB at 2xconcentrations for 5 minutes prior to the addition of compounds. Compounds (100x)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid