Found 51 of ic50 for monomerid = 55121 
Affinity DataIC50: 0nMAssay Description:Agonist required to inhibit Dopamine receptor D2 photoinactivation by 50% with Iodazidoclebopride using [3H]-SpiperoneMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibitory concentration half-maximal displacement of 1.0 nM [3H]NPA specific binding from rat striatal membranes using 10e-5 (+/-)ADTNMore data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataIC50: 2.10nMAssay Description:Inhibitory concentration for half-maximal displacement of 1.0 nM [3H]ADTN specific binding from rat striatal membranes using 10E-5 sulpirideMore data for this Ligand-Target Pair
Affinity DataIC50: 3.70nMAssay Description:Tested for binding to dopamine receptor using [3H]- ADTN as radioligand in calf caudate nucleus homogenates.More data for this Ligand-Target Pair
Affinity DataIC50: 4.5nMAssay Description:Tested for binding to dopamine receptor using [3H]apomorphine as radioligand in calf caudate nucleus homogenates.More data for this Ligand-Target Pair
Affinity DataIC50: 6.60nMAssay Description:Ability to inhibit the binding of [H]norepinephrine to NE receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:The IC50 value was reported as apparent, since [3H]NCA was purported to be irreversible. Result indicates the mean of two separate experiments, each ...More data for this Ligand-Target Pair
Affinity DataIC50: 64nMAssay Description:Inhibition of [3H]dopamine binding to Dopamine receptor in calf caudate nuclei.More data for this Ligand-Target Pair
Affinity DataIC50: 111nMAssay Description:Displacement of [3H]nemonapride from Rattus norvegicus (rat) wild type dopamine D3 receptor transfected in african green monkey COS7 cells after 1 hr...More data for this Ligand-Target Pair
Affinity DataIC50: 124nMAssay Description:Displacement of [3H]nemonapride from Rattus norvegicus (rat) chimeric dopamine D3 trunk/D3 tail receptor transfected in african green monkey COS7 cel...More data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of dopamine transporter-mediated [3H]dopamine uptake in Wistar rat striatal synaptosomes by liquid scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Compound was evaluated in vitro for its binding affinity towards Dopamine D1 receptor using [3H]-SCH- 23390 as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 460nMAssay Description:Inhibition of [3H]dopamine uptake in HEK cells expressing human DATMore data for this Ligand-Target Pair
Affinity DataIC50: 510nMAssay Description:Inhibitory binding activity against dopamine receptor using [3H]ADTN as the radioligand in striatal tissue of calf brain.More data for this Ligand-Target Pair
Affinity DataIC50: 530nMAssay Description:Inhibition of alpha-synuclein fibril formation (unknown origin) incubated for 6 days by thioflavin S based fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:Displacement of [3H]- #NAME? from binding Dopamine receptor D1 in rat striatumMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [3H]spiperone from high-affinity state of human dopamine D2L receptor transfected in HEK293 cells after 2 hrs by scintillation counti...More data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMAssay Description:Compound was for its ability to displace [3H]-haloperidol binding to rat striatal Dopamine receptor D2More data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+3nMAssay Description:Displacement of [3H]- -spiperone from Dopamine receptor D2 in rat striatumMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of [3H]haloperidol binding to Dopamine receptor in calf caudate nuclei.More data for this Ligand-Target Pair
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of 0.1 nM of [125I]- (S)-N-(1-Ethyl-pyrrolidin-2-ylmethyl)-5-iodo-2-methoxy-benzamide binding in striatal homogenates of rat brainMore data for this Ligand-Target Pair
Affinity DataIC50: 1.86E+3nMAssay Description:Inhibition of 0.1 nM of [125I]- (S)-N-(1-Ethyl-pyrrolidin-2-ylmethyl)-5-iodo-2-methoxy-benzamide binding in striatal homogenates of rat brainMore data for this Ligand-Target Pair
TargetM18 aspartyl aminopeptidase(Plasmodium falciparum 3D7)
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
Affinity DataIC50: 1.98E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
Affinity DataIC50: 2.20E+3nMAssay Description:Compound was evaluated for the inhibition of [3H]spiperone binding to Dopamine receptor D2 of rat striatal membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Compound was evaluated for the inhibition of [3H]-SCH- 23390 binding to Dopamine receptor D1 of rat striatal membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 3.05E+3nMAssay Description:Neuroleptic activity in terms of [3H]-spiroperidol binding in rat striatal membrane to Dopamine receptor D2More data for this Ligand-Target Pair
TargetDelta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1(Rattus norvegicus (rat))
Istituto Superiore Di Sanit£
Curated by ChEMBL
Istituto Superiore Di Sanit£
Curated by ChEMBL
Affinity DataIC50: 3.05E+3nMAssay Description:Ability to inhibit the specific binding of [3H]- dihydromorphine to opiate receptors in rat brain membrane preparation by 50%More data for this Ligand-Target Pair
Affinity DataIC50: 3.14E+3nMAssay Description:Displacement of [3H]nemonapride from Rattus norvegicus (rat) wild type dopamine D2 receptor transfected in african green monkey COS7 cells after 1 hr...More data for this Ligand-Target Pair
Affinity DataIC50: 3.26E+3nMAssay Description:Displacement of [3H]nemonapride from Rattus norvegicus (rat) chimeric dopamine D2 trunk/D2 tail receptor transfected in african green monkey COS7 cel...More data for this Ligand-Target Pair
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibitory activity against [3H]spiperone in Rat Striatal membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibitory activity against [3H]-SCH- 23390 in Rat Striatal membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 4.70E+3nMAssay Description:Displacement of [3H]-spiroperidol from homogenized bovine pituitary Dopamine receptor D2More data for this Ligand-Target Pair
Affinity DataIC50: 5.34E+3nMAssay Description:Concentration that produces 50 % displacement of specific [3H]spiroperidol binding to rat caudate membrane preparations.More data for this Ligand-Target Pair
Affinity DataIC50: 5.34E+3nMAssay Description:Inhibition of Rap1A-mediated geranylgeranylation expressed in mouse NIH3T3 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 7.10E+3nMAssay Description:Inhibition of human alpha-synuclein filament formation expressed in Escherichia coli BL21(DE3) cells incubated for 72 hrs by thioflavin S based fluor...More data for this Ligand-Target Pair
Affinity DataIC50: 8.00E+3nMAssay Description:Compound was evaluated in vitro for its binding affinity towards Dopamine D2 receptor using [3H]-spiperone as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Tested for binding to dopamine receptor using [3H]spiroperidol as radioligand in calf caudate nucleus homogenates.More data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of [3H]5-HT uptake in HEK cells expressing human SERTMore data for this Ligand-Target Pair
TargetProcathepsin L(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
Affinity DataIC50: >5.96E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
TargetSolute carrier family 22 member 3(Rattus norvegicus)
Medical College Of Georgia
Curated by ChEMBL
Medical College Of Georgia
Curated by ChEMBL
Affinity DataIC50: 6.20E+4nMAssay Description:TP_TRANSPORTER: inhibition of MPP+ uptake (MPP+: 1 uM) in OCT3-expressing HRPE cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 9.00E+4nMAssay Description:Ability to displace [3H]WB-4101 from rat brain alpha-1 adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of peptide EPQ (pY) EEIPI binding to Fyn protein kinase SH2 domain at 100 uM (no inhibition)More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Displacement of [3H]spiperone from low-affinity state of human dopamine D2L receptor transfected in HEK293 cells after 2 hrs by scintillation countin...More data for this Ligand-Target Pair
Affinity DataIC50: 1.28E+5nMAssay Description:Inhibition of recombinant bovine liver ARGI using L-arginine as substrate incubated for 60 mins by spectroscopic analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+5nMAssay Description:Inhibitory binding activity against dopamine receptor using [3H]spiperone as the radioligand in striatal tissue of calf brain.More data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of CMG2 (40 to 217) C175A and R40C double mutant (unknown origin) interaction to full length PA E733C mutant expressed in Escherichia coli...More data for this Ligand-Target Pair
TargetSolute carrier family 22 member 3(Rattus norvegicus)
Medical College Of Georgia
Curated by ChEMBL
Medical College Of Georgia
Curated by ChEMBL
Affinity DataIC50: 3.84E+5nMAssay Description:TP_TRANSPORTER: inhibition of TEA uptake (TEA: 20 uM) in OCT3-expressing HRPE cellsMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of Sprague-Dawley rat Bsep expressed in plasma membrane vesicles of Sf21 cells assessed as inhibition of ATP-dependent [3H]taurocholate up...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human BSEP expressed in plasma membrane vesicles of Sf21 cells assessed as inhibition of ATP-dependent [3H]taurocholate uptakeMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human BSEP expressed in baculovirus transfected fall armyworm Sf21 cell membranes vesicles assessed as reduction in ATP-dependent [3H]-...More data for this Ligand-Target Pair
