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Found 5 of ic50 for monomerid = 751
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandPNGBDBM751(CHEMBL289195 | Hydroxyethylene dipeptide isostere ...)
Affinity DataIC50:  0.420nMpH: 5.5 T: 2°CAssay Description:Assay of HIV protease inhibition was performed by peptide cleavage using the substrate Val-Ser-Gln-Asn-beta-naphthylalanine*Pro-Ile-Val. Products of ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM751(CHEMBL289195 | Hydroxyethylene dipeptide isostere ...)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of HIV-1 proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Sharp And Dohme Research Laboratories

LigandPNGBDBM751(CHEMBL289195 | Hydroxyethylene dipeptide isostere ...)
Affinity DataIC50:  0.600nMpH: 5.5 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Protease products were analyzed o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandPNGBDBM751(CHEMBL289195 | Hydroxyethylene dipeptide isostere ...)
Affinity DataIC50:  0.600nMpH: 5.5 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Protease products were analyzed o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
University Of Pennsylvania

LigandPNGBDBM751(CHEMBL289195 | Hydroxyethylene dipeptide isostere ...)
Affinity DataIC50:  0.600nMpH: 5.5 T: 2°CAssay Description:All enzyme assays were performed under initial velocity and steady-state conditions. The conditions for the enzyme catalyzed hydrolysis of the cleava...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed