Compile Data Set for Download or QSAR
maximum 50k data
Found 11 of ic50 for monomerid = 83449
TargetLysosomal Pro-X carboxypeptidase(Homo sapiens (Human))
G. D. Searle

Curated by ChEMBL
LigandPNGBDBM83449(1-(1-phenylcyclohexyl)piperidine;hydrochloride | M...)
Affinity DataIC50:  91nMAssay Description:Inhibition of [3H]1-[1-(2-thienyl) piperidine ([3H]TCP) binding to phencyclidine receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal Pro-X carboxypeptidase(Homo sapiens (Human))
G. D. Searle

Curated by ChEMBL
LigandPNGBDBM83449(1-(1-phenylcyclohexyl)piperidine;hydrochloride | M...)
Affinity DataIC50:  91nMAssay Description:Inhibition of [3H]-TCP binding to PCP receptor obtained from tissue homogenate preparation of fresh whole rat brain minus cerebellumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Homo sapiens (Human))
Glaxosmithkline Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM83449(1-(1-phenylcyclohexyl)piperidine;hydrochloride | M...)
Affinity DataIC50:  398nMAssay Description:Inhibition of human recombinant NR1/NR2A receptor expressed in U2OS assessed as change in intracellular calcium level by FLIPR assayMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(RAT)
G. D. Searle

Curated by ChEMBL
LigandPNGBDBM83449(1-(1-phenylcyclohexyl)piperidine;hydrochloride | M...)
Affinity DataIC50:  530nMAssay Description:Inhibition of [3H]- N-allylnormetazocine ([3H]NANM) binding to sigma receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
G. D. Searle

Curated by ChEMBL
LigandPNGBDBM83449(1-(1-phenylcyclohexyl)piperidine;hydrochloride | M...)
Affinity DataIC50:  530nMAssay Description:Inhibition of [3H]NANM binding to sigma receptor obtained from tissue homogenate preparation of fresh whole rat brain minus cerebellumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM83449(1-(1-phenylcyclohexyl)piperidine;hydrochloride | M...)
Affinity DataIC50:  560nMAssay Description:Inhibition of specific binding of [3H]3-PPP to sigma binding site in Guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM83449(1-(1-phenylcyclohexyl)piperidine;hydrochloride | M...)
Affinity DataIC50:  600nMAssay Description:Binding affinity against phencyclidine receptor was determined by the displacement of [3H]-TCP of whole rat brain minus cerebellum.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM83449(1-(1-phenylcyclohexyl)piperidine;hydrochloride | M...)
Affinity DataIC50:  868nMAssay Description:Inhibition of specific binding of [125I]-PIPAG to sigma binding site in Guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM83449(1-(1-phenylcyclohexyl)piperidine;hydrochloride | M...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of specific binding of [3H]DTG to sigma receptor in Guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM83449(1-(1-phenylcyclohexyl)piperidine;hydrochloride | M...)
Affinity DataIC50:  1.05E+3nMAssay Description:Inhibition of specific binding of [3H]DTG to sigma binding site in Guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Homo sapiens (Human))
Glaxosmithkline Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM83449(1-(1-phenylcyclohexyl)piperidine;hydrochloride | M...)
Affinity DataIC50:  1.26E+3nMAssay Description:Inhibition of human recombinant NR1/NR2B receptor expressed in U2OS assessed as change in intracellular calcium level by FLIPR assayMore data for this Ligand-Target Pair