Affinity DataIC50: 91nMAssay Description:Inhibition of [3H]1-[1-(2-thienyl) piperidine ([3H]TCP) binding to phencyclidine receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 91nMAssay Description:Inhibition of [3H]-TCP binding to PCP receptor obtained from tissue homogenate preparation of fresh whole rat brain minus cerebellumMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2A(Homo sapiens (Human))
Glaxosmithkline Medicines Research Centre
Curated by ChEMBL
Glaxosmithkline Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 398nMAssay Description:Inhibition of human recombinant NR1/NR2A receptor expressed in U2OS assessed as change in intracellular calcium level by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 530nMAssay Description:Inhibition of [3H]- N-allylnormetazocine ([3H]NANM) binding to sigma receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 530nMAssay Description:Inhibition of [3H]NANM binding to sigma receptor obtained from tissue homogenate preparation of fresh whole rat brain minus cerebellumMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute On Drug Abuse
Curated by ChEMBL
National Institute On Drug Abuse
Curated by ChEMBL
Affinity DataIC50: 560nMAssay Description:Inhibition of specific binding of [3H]3-PPP to sigma binding site in Guinea pig brain membranesMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
National Institute Of Diabetes
Curated by ChEMBL
National Institute Of Diabetes
Curated by ChEMBL
Affinity DataIC50: 600nMAssay Description:Binding affinity against phencyclidine receptor was determined by the displacement of [3H]-TCP of whole rat brain minus cerebellum.More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute On Drug Abuse
Curated by ChEMBL
National Institute On Drug Abuse
Curated by ChEMBL
Affinity DataIC50: 868nMAssay Description:Inhibition of specific binding of [125I]-PIPAG to sigma binding site in Guinea pig brain membranesMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute On Drug Abuse
Curated by ChEMBL
National Institute On Drug Abuse
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of specific binding of [3H]DTG to sigma receptor in Guinea pig brain membranesMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute On Drug Abuse
Curated by ChEMBL
National Institute On Drug Abuse
Curated by ChEMBL
Affinity DataIC50: 1.05E+3nMAssay Description:Inhibition of specific binding of [3H]DTG to sigma binding site in Guinea pig brain membranesMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2B(Homo sapiens (Human))
Glaxosmithkline Medicines Research Centre
Curated by ChEMBL
Glaxosmithkline Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of human recombinant NR1/NR2B receptor expressed in U2OS assessed as change in intracellular calcium level by FLIPR assayMore data for this Ligand-Target Pair