Compile Data Set for Download or QSAR
maximum 50k data
Found 14 of kd for monomerid = 21220
TargetAdenosine receptor A1(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM21220((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,...)
Affinity DataKd:  8.60nMAssay Description:Dissociation constant against Adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM21220((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,...)
Affinity DataKd:  9.10nMAssay Description:Binding affinity to A1R H251 6.52A mutant (unknown origin) by saturation NanoBRET binding assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetEndoplasmin(Sus scrofa)
Sloan-Kettering Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM21220((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,...)
Affinity DataKd:  200nMAssay Description:Binding affinity to porcine pancreas rough microsomal GRP94 after 1 hrMore data for this Ligand-Target Pair
TargetEndoplasmin(Sus scrofa)
Sloan-Kettering Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM21220((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,...)
Affinity DataKd:  200nMAssay Description:Displacement of [3H]NECA from GRP94 in porcine pancreas rough microsomes by liquid scintillation spectrometryMore data for this Ligand-Target Pair
TargetAdenosine receptor A1(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM21220((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,...)
Affinity DataKd:  214nMAssay Description:Binding affinity to wild type A1R (unknown origin) by saturation NanoBRET binding assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM21220((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,...)
Affinity DataKd:  234nMAssay Description:Inhibition of CA200645 binding to NanoLuc-fused human adenosine A1 receptor expressed in HEK293 cells assessed as kinetic dissociation constant by Na...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
University Of Bern

Curated by ChEMBL
LigandPNGBDBM21220((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,...)
Affinity DataKd:  295nMAssay Description:Inhibition of CA200645 binding to NanoLuc-fused rat adenosine A1 receptor expressed in HEK293 cells assessed as kinetic dissociation constant by Nano...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM21220((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,...)
Affinity DataKd:  490nMAssay Description:Binding affinity to A1R S267 7.32A mutant (unknown origin) in by saturation NanoBRET binding assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetEndoplasmin(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM21220((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,...)
Affinity DataKd:  530nMAssay Description:Displacement of FITC-geldanamycin from GRP94 (unknown origin) after 24 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetAdenosine receptor A1(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM21220((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,...)
Affinity DataKd:  575nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndoplasmin(Canis familiaris)
Shandong University

Curated by ChEMBL
LigandPNGBDBM21220((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,...)
Affinity DataKd:  2.80E+3nMAssay Description:Inhibition of N-terminal full length dog GRP94 (73 to 754 residues) expressed in Escherichia coli BL21(DE3) measured after 24 hrs by fluorescence pol...More data for this Ligand-Target Pair
TargetAdenosine receptor A1(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM21220((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,...)
Affinity DataKd:  4.17E+3nMAssay Description:Binding affinity to A1R E172 5.30A mutant (unknown origin) by saturation NanoBRET binding assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM21220((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,...)
Affinity DataKd:  1.40E+4nMAssay Description:Inhibition of human N-terminal His-tagged Hsp90alpha (1 to 236 residues) expressed in Escherichia coli BL21(DE3) measured after 24 hrs by fluorescenc...More data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM21220((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,...)
Affinity DataKd:  4.60E+4nMAssay Description:Displacement of FITC-geldanamycin from HSP90alpha (unknown origin) after 24 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair