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Compile Data Set for Download or QSAR

Found 2 hits of ki for monomerid = 17096   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Coagulation factor X


(Homo sapiens (Human))
BDBM17096
PNG
(3-chloro-N-{4-chloro-2-[(5-chloropyridin-2-yl)carb...)
Show SMILES COc1cc(Cl)cc(C(=O)Nc2ccc(Cl)cn2)c1NC(=O)c1scc(CN2CCCC2)c1Cl
Show InChI InChI=1S/C23H21Cl3N4O3S/c1-33-17-9-15(25)8-16(22(31)28-18-5-4-14(24)10-27-18)20(17)29-23(32)21-19(26)13(12-34-21)11-30-6-2-3-7-30/h4-5,8-10,12H,2-3,6-7,11H2,1H3,(H,29,32)(H,27,28,31)
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PC sid
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Similars

Article
PubMed
0.520 -52.5n/an/an/an/an/a7.522



Berlex Biosciences



Assay Description
The enzyme activities were determined kinetically as the initial rate of cleavage of a peptide p-nitroanilide. Km for enzyme and substrate was determ...


J Med Chem 50: 2967-80 (2007)


Article DOI: 10.1021/jm070125f
BindingDB Entry DOI: 10.7270/Q2J101F5
More data for this
Ligand-Target Pair
Thrombin and coagulation factor X


(Homo sapiens (Human))
BDBM17096
PNG
(3-chloro-N-{4-chloro-2-[(5-chloropyridin-2-yl)carb...)
Show SMILES COc1cc(Cl)cc(C(=O)Nc2ccc(Cl)cn2)c1NC(=O)c1scc(CN2CCCC2)c1Cl
Show InChI InChI=1S/C23H21Cl3N4O3S/c1-33-17-9-15(25)8-16(22(31)28-18-5-4-14(24)10-27-18)20(17)29-23(32)21-19(26)13(12-34-21)11-30-6-2-3-7-30/h4-5,8-10,12H,2-3,6-7,11H2,1H3,(H,29,32)(H,27,28,31)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
1.40E+3n/an/an/an/an/an/an/an/a



Berlex Biosciences



Assay Description
The enzyme activities were determined kinetically as the initial rate of cleavage of a peptide p-nitroanilide. Km for enzyme and substrate was determ...


J Med Chem 50: 2967-80 (2007)


Article DOI: 10.1021/jm070125f
BindingDB Entry DOI: 10.7270/Q2J101F5
More data for this
Ligand-Target Pair