Affinity DataKi: 0.200nMAssay Description:Binding affinity to human androgen receptor expressed in monkey COS7 cells by whole cell binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nM EC50: 5.10nMAssay Description:The compounds were evaluated in a transcriptional activation assay with hAR in a mammalian cell background (CV-1) as the primary in vitro assay. Rece...More data for this Ligand-Target Pair
Affinity DataKi: 0.200nM ΔG°: -57.6kJ/mole EC50: 5.10nMpH: 7.4 T: 2°CAssay Description:The compounds were evaluated in a transcriptional activation assay with hAR in a mammalian cell background (CV-1) as the primary in vitro assay. Rece...More data for this Ligand-Target Pair
Affinity DataKi: 0.200nM ΔG°: -57.6kJ/mole EC50: 5.10nMpH: 7.4 T: 2°CAssay Description:The compounds were evaluated in a transcriptional activation assay with hAR in a mammalian cell background (CV-1) as the primary in vitro assay. Rece...More data for this Ligand-Target Pair
Affinity DataKi: 0.270nM ΔG°: -50.8kJ/molepH: 7.4 T: 2°CAssay Description:The Ki values were determined by the application of the Cheng-Prusoff equation: Ki = (IC50 x Kd)/(Kd+[L]) where [L] is the concentration of [3H]MIB (...More data for this Ligand-Target Pair
Affinity DataKi: 0.280nM ΔG°: -50.7kJ/mole EC50: 1nMpH: 7.4 T: 2°CAssay Description:The Ki values were determined by the application of the Cheng-Prusoff equation: Ki = (IC50 x Kd)/(Kd+[L]) where [L] is the concentration of [3H]MIB (...More data for this Ligand-Target Pair
Affinity DataKi: 0.282nMAssay Description:Inhibition of [3H]mibolerone binding to cytosolic androgen receptor of rat ventral prostateMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nM ΔG°: -53.8kJ/mole EC50: 2.80nMpH: 7.4 T: 2°CAssay Description:Receptor Binding Assay (Ki)-Binding determined through direct displacement of ligand with [3H]-DHT in the MDA-453 cell line. Transactivation Assay (E...More data for this Ligand-Target Pair
Affinity DataKi: 0.300nM ΔG°: -56.5kJ/mole EC50: 5.70nMpH: 7.4 T: 2°CAssay Description:The compounds were evaluated in a transcriptional activation assay with hAR in a mammalian cell background (CV-1) as the primary in vitro assay. Rece...More data for this Ligand-Target Pair
Affinity DataKi: 0.430nM ΔG°: -49.7kJ/molepH: 7.4 T: 2°CAssay Description:The Ki values were determined by the application of the Cheng-Prusoff equation: Ki = (IC50 x Kd)/(Kd+[L]) where [L] is the concentration of [3H]MIB (...More data for this Ligand-Target Pair
Affinity DataKi: 0.690nMAssay Description:Inhibitory constant against rat prostate cytosol androgen receptor using [3H]miboleroneMore data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:Displacement of [3H]DHT from human Androgen receptor in human MDA-MB-453 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Agonist activity to the human androgen receptor (hAR) in CV-1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Binding affinity against Androgen receptor expressed COS cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Binding affinity towards human androgen receptor (hAR), using dihydrotestosterone as radioligand for competitive binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Transcriptional repression in HepG2 cells expressing human glucocorticoid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 4.70nMAssay Description:Displacement of [3H]DHT from human androgen receptor after 16 hrs by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Displacement of fluorescent-tagged R1881 from androgen receptor after 4 hrs by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 220nMAssay Description:Competitive inhibition of binding to human placental Cytochrome P450 19A1More data for this Ligand-Target Pair
Affinity DataKi: 1.20E+3nMAssay Description:Binding affinity to human CBG receptor (corticosteroid-binding globulins)More data for this Ligand-Target Pair
Affinity DataKi: 1.55E+3nMAssay Description:Inactivation rate (Ki) for human placental Cytochrome P450 19A1More data for this Ligand-Target Pair
TargetSolute carrier organic anion transporter family member(Danio rerio (Zebrafish))
Rudjer Boskovic Institute
Rudjer Boskovic Institute
Affinity DataKi: 2.34E+4nMAssay Description:In the inhibition experiments, the cells were preincubated for 20 s with test compounds, followed by a 5-min incubation with [3H]E3S (5 nM) or 30-min...More data for this Ligand-Target Pair