Found 50 of ki for monomerid = 23223 TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Wuhan University School Of Pharmaceutical Sciences
Curated by ChEMBL
Wuhan University School Of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 162nMAssay Description:Inhibition of FAM-Bid binding to human MCL1 expressed in Escherichia coli BL21 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKi: 170nMAssay Description:Displacement of FAM-Bim peptide from human Bcl2 by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Wuhan University School Of Pharmaceutical Sciences
Curated by ChEMBL
Wuhan University School Of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 180nMAssay Description:Inhibition of 5-FAM-QEDIIRNIARHLAQVGDSMDRSIPPG binding to Mcl-1 (unknown origin) preincubated for 30 mins followed by FAM-labeled peptide addition me...More data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Wuhan University School Of Pharmaceutical Sciences
Curated by ChEMBL
Wuhan University School Of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 180nMAssay Description:Binding affinity to MCL1More data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Wuhan University School Of Pharmaceutical Sciences
Curated by ChEMBL
Wuhan University School Of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 180nMAssay Description:Displacement of FAM-Bid from human Mcl1 by FP assayMore data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Wuhan University School Of Pharmaceutical Sciences
Curated by ChEMBL
Wuhan University School Of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 180nMAssay Description:Inhibition of MCl-1 (unknown origin)More data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Wuhan University School Of Pharmaceutical Sciences
Curated by ChEMBL
Wuhan University School Of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 180nMAssay Description:Binding affinity to Mc1-1 (unknown origin) by fluorescence polarization competition assayMore data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Wuhan University School Of Pharmaceutical Sciences
Curated by ChEMBL
Wuhan University School Of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 190nMAssay Description:Inhibition of FAM-Bid peptide binding to Mcl1 (unknown origin) expressed in Escherichia coli BL21 by fluorescence polarization-based binding assayMore data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Wuhan University School Of Pharmaceutical Sciences
Curated by ChEMBL
Wuhan University School Of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 190nMAssay Description:Displacement of FAM-Bid peptide from recombinant N-terminal His6x-tagged human Mcl-1 expressed in Escherichia coli BL21 (DE3) incubated for 30 mins b...More data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Wuhan University School Of Pharmaceutical Sciences
Curated by ChEMBL
Wuhan University School Of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 190nMAssay Description:Displacement of FAM-Bid BH3 peptide from recombinant Mcl-1 (unknown origin) expressed in Escherichia coli BL21 after 10 mins by fluorescence polariza...More data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Wuhan University School Of Pharmaceutical Sciences
Curated by ChEMBL
Wuhan University School Of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 200nMAssay Description:Inhibition of 6-carboxyfluorescein succinimidyl ester fluorescence tagged-Bid BH3 peptide (79 to 99 residues) binding to Mcl-1 (unknown origin) after...More data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Wuhan University School Of Pharmaceutical Sciences
Curated by ChEMBL
Wuhan University School Of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 260nMAssay Description:Displacement of FAM-Bid peptide from N-terminal 8x His-tagged MCl-1 (unknown origin) expressed in Escherichia coli BL21 (DE3) after 30 mins by fluore...More data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Wuhan University School Of Pharmaceutical Sciences
Curated by ChEMBL
Wuhan University School Of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 280nMAssay Description:Displacement of FAM-Bim peptide from human Mcl1 by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKi: 310nMAssay Description:Inhibition of 5-FAM-Bid peptide binding to Bcl-XL (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKi: 310nMAssay Description:Inhibition of Bcl-XL (unknown origin) using FAM-Bid peptide as substrate by fluorescence polarization-based assayMore data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Wuhan University School Of Pharmaceutical Sciences
Curated by ChEMBL
Wuhan University School Of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 310nMAssay Description:Inhibition of Mcl-1 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKi: 320nMAssay Description:Binding affinity to BCl2More data for this Ligand-Target Pair
Affinity DataKi: 320nMAssay Description:Displacement of FAM-Bid from human Bcl2 by FP assayMore data for this Ligand-Target Pair
Affinity DataKi: 320nMAssay Description:Inhibition of Bcl2 (unknown origin)More data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Wuhan University School Of Pharmaceutical Sciences
Curated by ChEMBL
Wuhan University School Of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 390nMAssay Description:Competitive binding affinity to Mcl-1 (unknown origin) using 5-FAM-Bid-BH3 peptide preincubated for 30 mins before 5-FAM-Bid-BH3 peptide addition and...More data for this Ligand-Target Pair
Affinity DataKi: 420nMAssay Description:Inhibition of 6-carboxyfluorescein succinimidyl ester fluorescence tagged-Bid BH3 peptide (79 to 99 residues) binding to Bcl-2 (unknown origin) after...More data for this Ligand-Target Pair
Affinity DataKi: 431nMAssay Description:Displacement of FAM-Bid peptide from N-terminal 8x His-tagged Bcl-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) after 30 mins by fluore...More data for this Ligand-Target Pair
Affinity DataKi: 440nMAssay Description:Inhibition of Bcl-2 (unknown origin) using FAM-Bid peptide as substrate by fluorescence polarization-based assayMore data for this Ligand-Target Pair
Affinity DataKi: 440nMAssay Description:Inhibition of 5-FAM-Bid peptide binding to Bcl-2 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKi: 450nMAssay Description:Inhibition of 5-FAM-QEDIIRNIARHLAQVGDSMDRSIPPG binding to Bcl-2 (unknown origin) preincubated for 30 mins followed by FAM-labeled peptide addition me...More data for this Ligand-Target Pair
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Shenyang Pharmaceutical University
Curated by ChEMBL
Shenyang Pharmaceutical University
Curated by ChEMBL
Affinity DataKi: 460nMAssay Description:Binding affinity to Bcl-2 (unknown origin) by fluorescence polarization competition assayMore data for this Ligand-Target Pair
Affinity DataKi: 480nMAssay Description:Displacement of FAM-Bak from human Bcl-xL by FP assayMore data for this Ligand-Target Pair
Affinity DataKi: 480nMAssay Description:Inhibition of Bcl-xL (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 480nMAssay Description:Binding affinity to Bcl-xlMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of New Mexico School Of Medicine
Curated by ChEMBL
University Of New Mexico School Of Medicine
Curated by ChEMBL
Affinity DataKi: 500nMAssay Description:The compound was tested for inhibitory activity against Aldose reductase from human placentaMore data for this Ligand-Target Pair
Affinity DataKi: 511nMAssay Description:Inhibition of FAM-Bid binding to human BCL2 expressed in Escherichia coli BL21 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKi: 558nMAssay Description:Displacement of FAM-Bid BH3 peptide from recombinant Bcl-2 (unknown origin) expressed in Escherichia coli BL21 after 10 mins by fluorescence polariza...More data for this Ligand-Target Pair
Affinity DataKi: 560nMAssay Description:Competitive binding affinity to Bcl-2 (unknown origin) using 5-FAM-Bid-BH3 peptide preincubated for 30 mins before 5-FAM-Bid-BH3 peptide addition and...More data for this Ligand-Target Pair
Affinity DataKi: 610nMAssay Description:Binding affinity to Bc1-xL (unknown origin) by fluorescence polarization competition assayMore data for this Ligand-Target Pair
Affinity DataKi: 620nMAssay Description:Inhibition of Bcl-XL (unknown origin) using 5-FAM-Bid-BH3 as substrate preincubated for 30 mins before substrate addition measured after 20 mins by f...More data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Wuhan University School Of Pharmaceutical Sciences
Curated by ChEMBL
Wuhan University School Of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 640nMAssay Description:Inhibition of 5-FAM-Bid peptide binding to MCL-1 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKi: 640nMAssay Description:Inhibition of Bcl-xL (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKi: 770nMAssay Description:Competitive binding affinity to Bcl-XL (unknown origin) using 5-FAM-Bid-BH3 peptide preincubated for 30 mins before 5-FAM-Bid-BH3 peptide addition an...More data for this Ligand-Target Pair
Affinity DataKi: 1.00E+3nMAssay Description:Inhibition of GST-tagged Bcl-xL (unknown origin) measured after 1 hr incubation by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetL-lactate dehydrogenase B chain(Mus musculus (Mouse))
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataKi: 1.40E+3nMAssay Description:Inhibition of mouse LDHB using sodium pyruvate as substrateMore data for this Ligand-Target Pair
Affinity DataKi: 1.40E+3nMAssay Description:Inhibition of 5-FAM-DMRPEIWIAQELRRIGDEFNAYYARR binding to Bcl-XL (unknown origin) preincubated for 30 mins followed by FAM-labeled peptide addition m...More data for this Ligand-Target Pair
TargetL-lactate dehydrogenase B chain(Homo sapiens (Human))
National Cancer Institute-Cro
Curated by ChEMBL
National Cancer Institute-Cro
Curated by ChEMBL
Affinity DataKi: 1.40E+3nMAssay Description:Competitive inhibition of human LDH1 in presence of NADHMore data for this Ligand-Target Pair
TargetSolute carrier organic anion transporter family member 1B1(Homo sapiens (Human))
Ku Leuven
Curated by ChEMBL
Ku Leuven
Curated by ChEMBL
Affinity DataKi: 1.78E+3nMAssay Description:Ki values for sodium fluorescein (10 uM) uptake in OATP1B1-transfected CHO cellsMore data for this Ligand-Target Pair
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataKi: 1.90E+3nMAssay Description:Inhibition of human LDHA using sodium pyruvate as substrateMore data for this Ligand-Target Pair
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataKi: 1.90E+3nMAssay Description:Competitive inhibition of human LDH5 in presence of NADHMore data for this Ligand-Target Pair
TargetSolute carrier organic anion transporter family member 1B3(Homo sapiens (Human))
Ku Leuven
Curated by ChEMBL
Ku Leuven
Curated by ChEMBL
Affinity DataKi: 3.47E+3nMAssay Description:Ki values for sodium fluorescein (10 uM) uptake in OATP1B3-transfected CHO cellsMore data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Wuhan University School Of Pharmaceutical Sciences
Curated by ChEMBL
Wuhan University School Of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 6.54E+3nMAssay Description:Inhibition of recombinant His6-tagged MCL1 (171-326) expressed in Escherichia coli BL21 (DE3) and Flu-Bak peptide interaction by fluorescence polariz...More data for this Ligand-Target Pair
Affinity DataKi: 1.01E+4nMAssay Description:Displacement of Flu-Bak peptide from recombinant antiapoptopic Bcl2 protein by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.77E+4nMAssay Description:Displacement of Flu-Bak peptide from recombinant antiapoptopic Bcl-w protein by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Dalian University Of Technology
Curated by ChEMBL
Dalian University Of Technology
Curated by ChEMBL
Affinity DataKi: >2.50E+4nMAssay Description:Displacement of FAM-p53TAD peptide from N-terminal 8x His-tagged human MDM2 (25 to 108 residues) expressed in Escherichia coli BL21 (DE3) after 30 mi...More data for this Ligand-Target Pair
