Affinity DataKi: 5.5nMAssay Description:Binding affinity of a compound to rat brain 5-hydroxytryptamine 1A (serotonin) receptor assayed by radiolabeled [3H]-8-OH-DPAT ligand displacementMore data for this Ligand-Target Pair
Affinity DataKi: 7.80nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
National Institute Of Neurological Disorders And Stroke
Curated by PDSP Ki Database
National Institute Of Neurological Disorders And Stroke
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
National Institute Of Neurological Disorders And Stroke
Curated by PDSP Ki Database
National Institute Of Neurological Disorders And Stroke
Curated by PDSP Ki Database
Affinity DataKi: 10nMAssay Description:Binding affinity of compound towards 5-hydroxytryptamine 1A receptor in rat striatal membranes by [3H]-OH-DPAT displacement.More data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Displacement of [3H]8-OH DPAT from rat 5HT1A receptor expressed in CHO cells after 30 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataKi: 13nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 7(GUINEA PIG)
Syntex Discovery Research
Curated by PDSP Ki Database
Syntex Discovery Research
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Stanford University
Curated by PDSP Ki Database
Stanford University
Curated by PDSP Ki Database
Affinity DataKi: 15nMAssay Description:Displacement of [125I]DOI from cloned human 5HT2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Affinity against 5-hydroxytryptamine 2A receptor (D) labeled with [125I]-DOI.More data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Effect on plasma amine oxidase (0.1 uM) after 0 min of incubation at pH 7.2More data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Affinity on 5-hydroxytryptamine 2 receptor labeled by [125I]DOIMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataKi: 16nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 6 receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataKi: 16nMAssay Description:Binding affinity against human 5-hydroxytryptamine 6 receptor stably transfected to HEK 293 human embryonic kidney cells using [3H]-lysergic acid die...More data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:Displacement of 2-[125I]-iodomelatonin from human melatonin receptor-2 transfected in CHO cell membranes after 120 minsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataKi: 20nMAssay Description:Binding affinity of the compound towards 5-hydroxytryptamine 1D receptor was determined in calf striatum homogenateMore data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Evaluated for the binding affinity to hippocampus striatal membranes at 5-hydroxytryptamine 1A receptor binding site by using [3H]-8-OH- DPAT as a ra...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
National Institute Of Neurological Disorders And Stroke
Curated by PDSP Ki Database
National Institute Of Neurological Disorders And Stroke
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
National Institute Of Neurological Disorders And Stroke
Curated by PDSP Ki Database
National Institute Of Neurological Disorders And Stroke
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
University Of Alberta
Curated by PDSP Ki Database
University Of Alberta
Curated by PDSP Ki Database
Affinity DataKi: 28nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor by vacuum filtrationMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataKi: 30nMAssay Description:Binding affinity of compound towards rodent 5-hydroxytryptamine 7 receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1F(Homo sapiens (Human))
Synaptic Pharmaceutical
Curated by PDSP Ki Database
Synaptic Pharmaceutical
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 1F(Homo sapiens (Human))
Synaptic Pharmaceutical
Curated by PDSP Ki Database
Synaptic Pharmaceutical
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
National Institute Of Neurological Disorders And Stroke
Curated by PDSP Ki Database
National Institute Of Neurological Disorders And Stroke
Curated by PDSP Ki Database
Affinity DataKi: 40nMAssay Description:Binding affinity at rat 5-hydroxytryptamine 7 receptor.More data for this Ligand-Target Pair
Affinity DataKi: 42nMAssay Description:Displacement of [125I]DOI from cloned human 5HT2C receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 50nMAssay Description:Evaluated for binding affinity towards rat cortical membranes at 5-hydroxytryptamine 1 receptor binding site by using [3H]-5-HT as a radioligand.More data for this Ligand-Target Pair
Affinity DataKi: 52nMAssay Description:Displacement of [125I]DOI from cloned human 5HT2B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 69nMAssay Description:Affinity of the compound on 5-hydroxytryptamine 1A receptor labeled by [3H]-8-OH-DPATMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataKi: 70nMpH: 7.4Assay Description:The h5-HT6 radioligand binding assays were performed as previously described. In brief, h5-HT6 cDNA was transiently expressed in HEK-293 cells using...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataKi: 78nMAssay Description:Binding affinity for human 5-hydroxytryptamine 6 receptor expressed in HEK 293 human embryonic kidney cells, [3H]-lysergic acid diethylamide as radio...More data for this Ligand-Target Pair
Affinity DataKi: 90nMAssay Description:Binding affinity (Ki) to rat cortical membranes at 5-HT1B binding site by using [125 I] ICYP as a radioligand.More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Stanford University
Curated by PDSP Ki Database
Stanford University
Curated by PDSP Ki Database
Affinity DataKi: 92nMAssay Description:Displacement of [3H]DOB from rat 5HT2A receptor expressed in mouse NIH/3T3 cells after 30 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 7(GUINEA PIG)
Syntex Discovery Research
Curated by PDSP Ki Database
Syntex Discovery Research
Curated by PDSP Ki Database
Affinity DataKi: 210nMAssay Description:Displacement of 2-[125I]-iodomelatonin from human melatonin receptor-1 transfected in CHO cell membranes after 120 minsMore data for this Ligand-Target Pair
Affinity DataKi: 350nMAssay Description:Evaluated for binding affinity towards 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
Affinity DataKi: 390nMAssay Description:Binding affinity to rat cortical membranes at 5-hydroxytryptamine 2 (5-HT2) receptor using [3H]KET as a radioligandMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1E(Homo sapiens (Human))
University Of Alberta
Curated by PDSP Ki Database
University Of Alberta
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 1E(Homo sapiens (Human))
University Of Alberta
Curated by PDSP Ki Database
University Of Alberta
Curated by PDSP Ki Database
Affinity DataKi: 620nMAssay Description:Effect on plasma amine oxidase (0.1 uM) after 15 min of incubation at pH 7.2More data for this Ligand-Target Pair
Affinity DataKi: 620nMAssay Description:Affinity against 5-hydroxytryptamine 2A receptor (K) labeled with [3H]-ketanserin.More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataKi: 960nMAssay Description:Affinity against 5-hydroxytryptamine 2C receptor in J1 cells transfected with the rat 5-HT2C gene labeled with [3H]-mesulergine.More data for this Ligand-Target Pair
Affinity DataKi: 1.20E+3nMAssay Description:Binding affinity to 5-hydroxytryptamine 2 receptor in rat frontal cortical membranes by [3H]- KET displacement.More data for this Ligand-Target Pair