Affinity DataKi: 6.60nMAssay Description:Displacement of [3H]GR113808 from 5-HT4R in guinea pig brain membranes incubated for 30 mins by radioligand binding assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Jining Medical University
Curated by ChEMBL
Jining Medical University
Curated by ChEMBL
Affinity DataKi: 6.60nMAssay Description:Displacement of [3H]GR113808 from human 5-HT4R membrane in Tris buffer assessed as inhibitory constant measured after 60 mins by filter binding metho...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Jining Medical University
Curated by ChEMBL
Jining Medical University
Curated by ChEMBL
Affinity DataKi: 7.10nMAssay Description:Prior to these competition studies, a series of saturation curves were performed in order to check whether the pharmacological parameters Kd, Bmax an...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Jining Medical University
Curated by ChEMBL
Jining Medical University
Curated by ChEMBL
Affinity DataKi: 9.5nMAssay Description:Displacement of [3H]-GR113808 from recombinant human 5-HT4BR expressed in membranes after 60 minsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Jining Medical University
Curated by ChEMBL
Jining Medical University
Curated by ChEMBL
Affinity DataKi: 10nMAssay Description:Displacement of [3H]GR113808 from human 5-HT4 receptor expressed in Chem-1 cell membrane incubated for 60 mins by radiometric scintillation counting ...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Jining Medical University
Curated by ChEMBL
Jining Medical University
Curated by ChEMBL
Affinity DataKi: 10nMAssay Description:Agonist activity at 5-HT4R (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Normandie Univ
Curated by ChEMBL
Normandie Univ
Curated by ChEMBL
Affinity DataKi: 51nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma-1 receptor in human Jurkat cell membranes after 2 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair