Compile Data Set for Download or QSAR
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Found 8 of ki for monomerid = 50079362
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Cermn

Curated by ChEMBL
LigandPNGBDBM50079362(CHEMBL3417009 | US9663465, 9)
Affinity DataKi:  6.60nMAssay Description:Displacement of [3H]GR113808 from 5-HT4R in guinea pig brain membranes incubated for 30 mins by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Jining Medical University

Curated by ChEMBL
LigandPNGBDBM50079362(CHEMBL3417009 | US9663465, 9)
Affinity DataKi:  6.60nMAssay Description:Displacement of [3H]GR113808 from human 5-HT4R membrane in Tris buffer assessed as inhibitory constant measured after 60 mins by filter binding metho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Jining Medical University

Curated by ChEMBL
LigandPNGBDBM50079362(CHEMBL3417009 | US9663465, 9)
Affinity DataKi:  7.10nMAssay Description:Prior to these competition studies, a series of saturation curves were performed in order to check whether the pharmacological parameters Kd, Bmax an...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Jining Medical University

Curated by ChEMBL
LigandPNGBDBM50079362(CHEMBL3417009 | US9663465, 9)
Affinity DataKi:  9.5nMAssay Description:Displacement of [3H]-GR113808 from recombinant human 5-HT4BR expressed in membranes after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Jining Medical University

Curated by ChEMBL
LigandPNGBDBM50079362(CHEMBL3417009 | US9663465, 9)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]GR113808 from human 5-HT4 receptor expressed in Chem-1 cell membrane incubated for 60 mins by radiometric scintillation counting ...More data for this Ligand-Target Pair
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Jining Medical University

Curated by ChEMBL
LigandPNGBDBM50079362(CHEMBL3417009 | US9663465, 9)
Affinity DataKi:  10nMAssay Description:Agonist activity at 5-HT4R (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50079362(CHEMBL3417009 | US9663465, 9)
Affinity DataKi:  16nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50079362(CHEMBL3417009 | US9663465, 9)
Affinity DataKi:  51nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma-1 receptor in human Jurkat cell membranes after 2 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed