Compile Data Set for Download or QSAR
maximum 50k data
Found 7 of ki for monomerid = 50245853
TargetActivated CDC42 kinase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50245853(CHEMBL502156 | N3-(2,6-dimethylphenyl)-N6-(3-fluor...)
Affinity DataKi:  3nMAssay Description:Inhibition of histidine-tagged ACK1 (amino acids 117 to 489) (unknown origin) expressed in SF9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50245853(CHEMBL502156 | N3-(2,6-dimethylphenyl)-N6-(3-fluor...)
Affinity DataKi:  11nMAssay Description:Inhibition of LCK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivated CDC42 kinase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50245853(CHEMBL502156 | N3-(2,6-dimethylphenyl)-N6-(3-fluor...)
Affinity DataKi:  20nMAssay Description:Inhibition of flag-tagged ACK1 (unknown origin) autophosphorylation expressed in human 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50245853(CHEMBL502156 | N3-(2,6-dimethylphenyl)-N6-(3-fluor...)
Affinity DataKi:  125nMAssay Description:Inhibition of BTK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50245853(CHEMBL502156 | N3-(2,6-dimethylphenyl)-N6-(3-fluor...)
Affinity DataKi: >2.50E+3nMAssay Description:Inhibition of Tie2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50245853(CHEMBL502156 | N3-(2,6-dimethylphenyl)-N6-(3-fluor...)
Affinity DataKi: >1.25E+4nMAssay Description:Inhibition of KDR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50245853(CHEMBL502156 | N3-(2,6-dimethylphenyl)-N6-(3-fluor...)
Affinity DataKi: >1.25E+4nMAssay Description:Inhibition of Jak3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed