Found 4 Enz. Inhib. hit(s) with Target = '11-beta-hydroxysteroid dehydrogenase 1' and Ligand = 'BDBM50448696'
Affinity DataIC50: 8.10nMAssay Description:Inhibition of recombinant human 11beta-HSD1 using cortisone/[3H]-cortisone as substrate after 5 hrs by reverse-phase HPLC analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of N-terminal 6-His-tagged full-length mouse 11beta-HSD1 assessed as conversion of cortisone to cortisol after 25 mins by competitive HTRF...More data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibition of N-terminal 6-His-tagged full-length human 11beta-HSD1 assessed as conversion of cortisone to cortisol after 25 mins by competitive HTRF...More data for this Ligand-Target Pair
Affinity DataIC50: 55nMAssay Description:Inhibition of rat 11beta-HSD1 assessed as conversion of cortisone to cortisol after 25 mins by competitive HTRF assayMore data for this Ligand-Target Pair