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Found 3 Enz. Inhib. hit(s) with Target = '5'-nucleotidase' and Ligand = 'BDBM435853'
Target5'-nucleotidase(Homo sapiens (Human))
Calithera Biosciences

US Patent
LigandPNGBDBM435853(US10570167, Cpd. # 179 | US11034715, Cpd. # 179)
Affinity DataIC50:  9nMAssay Description:For measurements of soluble CD73 enzyme activity, recombinant CD73 was obtained from R&D Systems, Cat. No. 5795-EN-010. Serial dilutions of test comp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5'-nucleotidase(Homo sapiens (Human))
Calithera Biosciences

US Patent
LigandPNGBDBM435853(US10570167, Cpd. # 179 | US11034715, Cpd. # 179)
Affinity DataIC50:  9nMAssay Description:Inhibition of human C-terminal 6His-tagged CD73 ( Trp27 to Lys547 residues) expressed in CHO cells using AMP as substrate incubated for 30 mins by ma...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5'-nucleotidase(Homo sapiens (Human))
Calithera Biosciences

US Patent
LigandPNGBDBM435853(US10570167, Cpd. # 179 | US11034715, Cpd. # 179)
Affinity DataIC50:  9nMAssay Description:For measurements of soluble CD73 enzyme activity, recombinant CD73 was obtained from R&D Systems, Cat. No. 5795-EN-010. Serial dilutions of test comp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent