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Found 2 Enz. Inhib. hit(s) with Target = 'Acetyl-CoA carboxylase 1' and Ligand = 'BDBM50439643'
TargetAcetyl-CoA carboxylase 1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM50439643(CHEMBL2419598 | US8993586, 76)
Affinity DataIC50:  5.60nMpH: 7.5Assay Description:Preparation of rhACC1. Two liters of SF9 cells, infected with recombinant baculovirus containing full length human ACC1 cDNA, were suspended in ice-c...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAcetyl-CoA carboxylase 1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM50439643(CHEMBL2419598 | US8993586, 76)
Affinity DataIC50:  6nMAssay Description:Inhibition of human ACC1 using acetyl-CoA as substrate assessed as [14C]malonyl-CoA synthesis preincubated for 10 mins prior to substrate addition me...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed