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Found 3 Enz. Inhib. hit(s) with Target = 'Acetylcholinesterase' and Ligand = 'BDBM10589'
TargetAcetylcholinesterase(Homo sapiens (Human))
Universitat De Barcelona

LigandPNGBDBM10589(3-Chloro-6,7,10,11-tetrahydro-9-methyl-12-{{8-[(6-...)
Affinity DataIC50:  0.400nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Universitat De Barcelona

LigandPNGBDBM10589(3-Chloro-6,7,10,11-tetrahydro-9-methyl-12-{{8-[(6-...)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 20 mins prior substrate addition measured after 5 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Bos taurus (bovine))
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM10589(3-Chloro-6,7,10,11-tetrahydro-9-methyl-12-{{8-[(6-...)
Affinity DataIC50:  263nMAssay Description:Inhibition of bovine AChE-induced coumarin-tagged PrP106-126 aggregation after 48 hrs by fluorescence microscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed