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Found 31 Enz. Inhib. hit(s) with Target = 'Acetylcholinesterase' and Ligand = 'BDBM50199522'
TargetAcetylcholinesterase(Tetronarce californica (Pacific electric ray) (Tor...)
The Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50199522((+)-huperzine A | (+-)-HA | (-)-1-Amino-13-ethylid...)
Affinity DataIC50:  11.4nMAssay Description:Inhibition of Torpedo california AChE by Ellman's methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
The Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50199522((+)-huperzine A | (+-)-HA | (-)-1-Amino-13-ethylid...)
Affinity DataIC50:  21nMAssay Description:Inhibition of human AChE by Ellman's methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
The Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50199522((+)-huperzine A | (+-)-HA | (-)-1-Amino-13-ethylid...)
Affinity DataIC50:  33nMAssay Description:Inhibition of human AChE using acetylthiocholine iodide as substrate measured for 1 min by Ellman's methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
The Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50199522((+)-huperzine A | (+-)-HA | (-)-1-Amino-13-ethylid...)
Affinity DataIC50:  45nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
The Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50199522((+)-huperzine A | (+-)-HA | (-)-1-Amino-13-ethylid...)
Affinity DataIC50:  47nMAssay Description:Inhibitory concentration against human erythrocyte AcetylcholinesteraseMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50199522((+)-huperzine A | (+-)-HA | (-)-1-Amino-13-ethylid...)
Affinity DataIC50:  53nMAssay Description:In vitro inhibitory concentration against rat cortex acetylcholinesteraseMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Bos taurus (bovine))
Hoshi University

Curated by ChEMBL
LigandPNGBDBM50199522((+)-huperzine A | (+-)-HA | (-)-1-Amino-13-ethylid...)
Affinity DataIC50:  53nMAssay Description:Inhibition of bovine acetylcholinesteraseMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50199522((+)-huperzine A | (+-)-HA | (-)-1-Amino-13-ethylid...)
Affinity DataIC50:  65nMAssay Description:Inhibition of AChE in Sprague-Dawley rat cortices using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50199522((+)-huperzine A | (+-)-HA | (-)-1-Amino-13-ethylid...)
Affinity DataIC50:  72.4nMpH: 5.0Assay Description:Inhibition of AChE in rat cortex at pH 5More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Bos taurus (bovine))
Hoshi University

Curated by ChEMBL
LigandPNGBDBM50199522((+)-huperzine A | (+-)-HA | (-)-1-Amino-13-ethylid...)
Affinity DataIC50:  74nMAssay Description:In vitro inhibitory concentration against bovine acetylcholinesterase enzymeMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Bos taurus (bovine))
Hoshi University

Curated by ChEMBL
LigandPNGBDBM50199522((+)-huperzine A | (+-)-HA | (-)-1-Amino-13-ethylid...)
Affinity DataIC50:  74nMAssay Description:Inhibition of acetylcholinesterase (AChE)activity in bovine erythrocytesMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Bos taurus (bovine))
Hoshi University

Curated by ChEMBL
LigandPNGBDBM50199522((+)-huperzine A | (+-)-HA | (-)-1-Amino-13-ethylid...)
Affinity DataIC50:  74nMAssay Description:Compound was evaluated for the inhibition of acetylcholinesterase of bovine erythrocytesMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Bos taurus (bovine))
Hoshi University

Curated by ChEMBL
LigandPNGBDBM50199522((+)-huperzine A | (+-)-HA | (-)-1-Amino-13-ethylid...)
Affinity DataIC50:  74nMAssay Description:Inhibition of bovine AChE by Ellman's methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Bos taurus (bovine))
Hoshi University

Curated by ChEMBL
LigandPNGBDBM50199522((+)-huperzine A | (+-)-HA | (-)-1-Amino-13-ethylid...)
Affinity DataIC50:  74nMAssay Description:Inhibition of bovine erythrocyte AChEMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50199522((+)-huperzine A | (+-)-HA | (-)-1-Amino-13-ethylid...)
Affinity DataIC50:  82nMAssay Description:Inhibition of rat cortex homogenate acetylcholinesterase by spectrophotometric methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50199522((+)-huperzine A | (+-)-HA | (-)-1-Amino-13-ethylid...)
Affinity DataIC50:  82nMAssay Description:Inhibition of rat cortex AChE using acetylthiocholine iodide as substrate measured after 20 mins by Ellman's methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50199522((+)-huperzine A | (+-)-HA | (-)-1-Amino-13-ethylid...)
Affinity DataIC50:  98nMAssay Description:Inhibition of AChE in rat cortex homogenate using acetylthiocholine iodide as substrate after 20 mins by Ellman's methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Bos taurus (bovine))
Hoshi University

Curated by ChEMBL
LigandPNGBDBM50199522((+)-huperzine A | (+-)-HA | (-)-1-Amino-13-ethylid...)
Affinity DataIC50:  100nMAssay Description:Inhibition of bovine erythrocytes AChE using acetylthiocholine iodide as substrate incubated for 15 to 20 mins by Ellman's methodsMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50199522((+)-huperzine A | (+-)-HA | (-)-1-Amino-13-ethylid...)
Affinity DataIC50:  120nMAssay Description:Inhibition of rat cortex AChE using acetylthiocholine iodide as substrate after 20 mins by by Ellman's methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50199522((+)-huperzine A | (+-)-HA | (-)-1-Amino-13-ethylid...)
Affinity DataIC50:  120nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine chloride as substrate after 15 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
The Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50199522((+)-huperzine A | (+-)-HA | (-)-1-Amino-13-ethylid...)
Affinity DataIC50:  260nMAssay Description:Inhibition of human erythrocyte AChEMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
The Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50199522((+)-huperzine A | (+-)-HA | (-)-1-Amino-13-ethylid...)
Affinity DataIC50:  260nMAssay Description:Inhibition of acetylcholinesterase isolated from Human erythrocytes.More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
The Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50199522((+)-huperzine A | (+-)-HA | (-)-1-Amino-13-ethylid...)
Affinity DataIC50:  260nMAssay Description:In vitro inhibitory concentration against acetylcholinesterase of human erythrocytesMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
The Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50199522((+)-huperzine A | (+-)-HA | (-)-1-Amino-13-ethylid...)
Affinity DataIC50:  400nMAssay Description:Inhibition of AChE (unknown origin) using acetylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition measured afte...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
The Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50199522((+)-huperzine A | (+-)-HA | (-)-1-Amino-13-ethylid...)
Affinity DataIC50:  600nMAssay Description:Inhibition of human acetylcholinesterase after 30 mins by microplate reader-based Ellman's methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
The Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50199522((+)-huperzine A | (+-)-HA | (-)-1-Amino-13-ethylid...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of AChE by Ellman's methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
The Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50199522((+)-huperzine A | (+-)-HA | (-)-1-Amino-13-ethylid...)
Affinity DataIC50:  4.30E+3nMAssay Description:Inhibition of AChE (unknown origin) using acetylthiocholine iodide as substrate after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50199522((+)-huperzine A | (+-)-HA | (-)-1-Amino-13-ethylid...)
Affinity DataIC50:  5.17E+3nMAssay Description:Inhibition of Electric eel AChE using acetylcholine iodide as substrate by spectrophotometry based Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
The Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50199522((+)-huperzine A | (+-)-HA | (-)-1-Amino-13-ethylid...)
Affinity DataIC50:  5.28E+3nMAssay Description:Inhibition of AChE (unknown origin) using acetylthiocholine iodide as substrate by DTNB reagent based Ellman's methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50199522((+)-huperzine A | (+-)-HA | (-)-1-Amino-13-ethylid...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine chloride as a substrate incubated for 20 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
The Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50199522((+)-huperzine A | (+-)-HA | (-)-1-Amino-13-ethylid...)
Affinity DataKd:  17nMAssay Description:Binding affinity to CM5 sensor chip immobilized recombinant human AChE assessed as dissociation constant at 298.15 K by surface plasmon resonance ass...More data for this Ligand-Target Pair