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Found 6 Enz. Inhib. hit(s) with Target = 'Activin receptor type-1' and Ligand = 'BDBM102619'
TargetActivin receptor type-1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM102619(K02288a | US10688093, Compound 382_0087_0284 | US1...)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of GST-tagged human recombinant ALK2 (145 to 509 residues) expressed in baculovirus expression system using casein as substrate in presenc...More data for this Ligand-Target Pair
TargetActivin receptor type-1(Mus musculus)
Massachusetts Institute Of Technology

LigandPNGBDBM102619(K02288a | US10688093, Compound 382_0087_0284 | US1...)
Affinity DataIC50:  1.20nMMore data for this Ligand-Target Pair
TargetActivin receptor type-1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM102619(K02288a | US10688093, Compound 382_0087_0284 | US1...)
Affinity DataIC50:  35nMAssay Description:Inhibition of human recombinant human ALK2 kinase after 45 mins by liquid scintillation counting in presence of ATP [gamma-32P]More data for this Ligand-Target Pair
TargetActivin receptor type-1(Mus musculus)
Massachusetts Institute Of Technology

LigandPNGBDBM102619(K02288a | US10688093, Compound 382_0087_0284 | US1...)
Affinity DataIC50:  230nMAssay Description:Inhibition of BMP2-induced BMP receptor type 1 ALK2 in mouse C2C12 cells after 30 mins by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetActivin receptor type-1(Mus musculus)
Massachusetts Institute Of Technology

LigandPNGBDBM102619(K02288a | US10688093, Compound 382_0087_0284 | US1...)
Affinity DataIC50:  340nMAssay Description:Inhibition of BMP4-induced BMP receptor in mouse C2C12 cells after 30 mins by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetActivin receptor type-1(Mus musculus)
Massachusetts Institute Of Technology

LigandPNGBDBM102619(K02288a | US10688093, Compound 382_0087_0284 | US1...)
Affinity DataIC50:  420nMAssay Description:Inhibition of BMP6-induced BMP receptor type 1 ALK2 in mouse C2C12 cells after 30 mins by luciferase reporter gene assayMore data for this Ligand-Target Pair