Compile Data Set for Download or QSAR
maximum 50k data
Found 4 Enz. Inhib. hit(s) with Target = 'Adenosine receptor A2a' and Ligand = 'BDBM50382491'
TargetAdenosine receptor A2a(Homo sapiens (Human))
Heptares Therapeutics

US Patent
LigandPNGBDBM50382491(CHEMBL2024114 | US10988455, Example 1(xlii))
Affinity DataKi:  1.38nMAssay Description:All test compounds were prepared as a stock solution of 10 mM in 100% DMSO.Inhibition binding assays were performed using 2.5 μg of membranes pr...More data for this Ligand-Target Pair
TargetAdenosine receptor A2a(Homo sapiens (Human))
Heptares Therapeutics

US Patent
LigandPNGBDBM50382491(CHEMBL2024114 | US10988455, Example 1(xlii))
Affinity DataKi:  1.41nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2A receptor expressed in HEK293 cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
TargetAdenosine receptor A2a(Homo sapiens (Human))
Heptares Therapeutics

US Patent
LigandPNGBDBM50382491(CHEMBL2024114 | US10988455, Example 1(xlii))
Affinity DataKi:  4nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2A receptor expressed in HEK293 cell membrane incubated for 1 hr by microplate beta scintillation ...More data for this Ligand-Target Pair
TargetAdenosine receptor A2a(Homo sapiens (Human))
Heptares Therapeutics

US Patent
LigandPNGBDBM50382491(CHEMBL2024114 | US10988455, Example 1(xlii))
Affinity DataKi:  4nMAssay Description:Antagonist activity at adenosine A2A receptor (unknown origin)More data for this Ligand-Target Pair