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Found 4 Enz. Inhib. hit(s) with Target = 'Adenosine receptor A3' and Ligand = 'BDBM50170941'
TargetAdenosine receptor A3(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50170941(2-p-Tolyl-2,5-dihydro-pyrazolo[4,3-c]quinolin-4-on...)
Affinity DataKi:  9nMAssay Description:Inhibition of [3H]-MRE3008-F20 binding to human adenosine A3 receptor expressed in CHO cells; (n=3 - 6)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50170941(2-p-Tolyl-2,5-dihydro-pyrazolo[4,3-c]quinolin-4-on...)
Affinity DataKi:  9nMAssay Description:Displacement of [125I]I-AB-MECA from human recombinant adenosine A3 receptor expressed in CHO cells after 60 mins by gamma counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50170941(2-p-Tolyl-2,5-dihydro-pyrazolo[4,3-c]quinolin-4-on...)
Affinity DataKi:  34nMAssay Description:Inhibition of cAMP accumulation in human adenosine A3 receptor assay as inhibition of Cl-IB-MECAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50170941(2-p-Tolyl-2,5-dihydro-pyrazolo[4,3-c]quinolin-4-on...)
Affinity DataIC50:  34nMAssay Description:Antagonist activity at human adenosine A3 receptor expressed in CHO cells assessed as blockade of Cl-IB-MECA-mediated inhibition of forskolin-stimula...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed