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Found 4 Enz. Inhib. hit(s) with Target = 'Alkaline phosphatase, tissue-nonspecific isozyme' and Ligand = 'BDBM18073'
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM18073((2S)-2-amino-3-phenylpropanoic acid | CHEMBL301523...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of TNAP by analogous luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Bos taurus (Cattle))
University Of Karachi

LigandPNGBDBM18073((2S)-2-amino-3-phenylpropanoic acid | CHEMBL301523...)
Affinity DataIC50:  8.02E+4nMpH: 9.8 T: 2°CAssay Description:Alkaline phosphatase (b-TNAP, c-IAP purchased from Calzyme Laboratories, Inc. USA) inhibition assay of different cyclic sulfonamides was performed us...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM18073((2S)-2-amino-3-phenylpropanoic acid | CHEMBL301523...)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibition of human TNAP using CDP-star as substrate pretreated for 10 mins followed by substrate addition measured after 10 mins by spectrophotometr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM18073((2S)-2-amino-3-phenylpropanoic acid | CHEMBL301523...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of human TNAP expressed in African green monkey COS7 cell membranes using CDP-star as substrate pretreated for 5 to 10 mins followed by su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed