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Found 3 Enz. Inhib. hit(s) with Target = 'Apelin receptor' and Ligand = 'BDBM50172368'
TargetApelin receptor(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50172368(CHEMBL3809335)
Affinity DataKi:  0.340nMAssay Description:Displacement of [125I]-Apelin-13[Glp65, Nle75, Tyr77] from YFP epitope-tagged human APJ expressed in HEK-293 cells after 1 hr by gamma counting metho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApelin receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50172368(CHEMBL3809335)
Affinity DataEC50:  6.80nMAssay Description:Agonist activity at human APJ receptor expressed in HEK-293 cells assessed as dissociation of G-alpha-i1 protein after 5 mins by BRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApelin receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50172368(CHEMBL3809335)
Affinity DataEC50:  106nMAssay Description:Agonist activity at human APJ receptor expressed in HEK-293 cells assessed as beta-arrestin2 recruitment after 30 mins by BRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed