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Found 2 Enz. Inhib. hit(s) with Target = 'Aurora kinase A' and Ligand = 'BDBM247371'
TargetAurora kinase A(Homo sapiens (Human))
Cancer Research Technology

US Patent
LigandPNGBDBM247371(US9447092, 1)
Affinity DataIC50:  38nMAssay Description:Myc-tagged Aurora A was transfected in Hela cells using Lipofectamine LTX in 24 well plates, and 24 hours after transfection, cells were treated with...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens (Human))
Cancer Research Technology

US Patent
LigandPNGBDBM247371(US9447092, 1)
Affinity DataKd:  7.5nMAssay Description:The kinase selectivity was assessed by profiling Example 1 in a 442-kinase panel (386 non-mutant kinases) at a concentration of 1 μM using the K...More data for this Ligand-Target Pair
In DepthDetails US Patent