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Found 2 Enz. Inhib. hit(s) with Target = 'Aurora kinase A' and Ligand = 'BDBM50394785'
TargetAurora kinase A(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50394785(CHEMBL2163404)
Affinity DataIC50:  1nMAssay Description:Inhibition of Aurora kinase A autophosphorylation in human HEK293 cells after 2 hrs by phosphor antibody readout assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50394785(CHEMBL2163404)
Affinity DataKd:  5.80nMAssay Description:Binding affinity to Aurora kinase A catalytic domain by competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed