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Found 2 Enz. Inhib. hit(s) with Target = 'Bcl-2-like protein 1' and Ligand = 'BDBM209215'
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM209215(US9266877, 161)
Affinity DataKi: <0.100nM ΔG°: <-57.1kJ/moleT: 2°CAssay Description:The measurement of competition of compounds of Formula (I) with F-Bak for a Bcl-2 family protein (Bcl-xL) binding site using a Time Resolved Fluoresc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBcl-2-like protein 1(Mus musculus (Mouse))
Abbvie

US Patent
LigandPNGBDBM209215(US9266877, 161)
Affinity DataEC50:  7nMAssay Description:The efficacy of the compounds of Formula (I) can also be determined in cell-based killing assays using a variety of cell lines and mouse tumor models...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent