Affinity DataKi: 2.80E+3nMAssay Description:Inhibition of Bcl-xL (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3.69E+3nMT: 2°CAssay Description:A Bak BH3 peptide (F-BakBH3) (GQVGRQLAIIGDDINR) was labeled at the N-terminus with fluorescein isothiocyanate (FITC) (Molecular Probes) and purified ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.70E+3nM Kd: 1.70E+3nMpH: 7.4 T: 2°CAssay Description:FPAs were performed using various concentrations of GST-Bcl-2 family proteins, incubated with FITC-conjugated peptide substrates in the presence of i...More data for this Ligand-Target Pair
Affinity DataKd: 1.70E+3nMpH: 7.4Assay Description:Titrations were performed using a VP-ITC or ITC200 calorimeter from Microcal (Northampton, Mass.). BCL-XL was used at concentrations between 25 and 1...More data for this Ligand-Target Pair