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Found
1
Enz. Inhib. hit(s) with Target = 'Beta-secretase 1' and Ligand = 'BDBM335448'
Target
Beta-secretase 1
(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Ligand
BDBM335448
((3R,6S)-5-amino-3-(5-((3-(but- 2-yn-1-yloxy)-1,7-n...)
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Affinity Data
Ki: 0.910nM
Assay Description:
The compounds of the invention were determined to be potent inhibitors of BACE-1 using the following assay.The following reagents were used in this a...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
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Ligand Info
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In Depth
Details
US Patent
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