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Found 2 Enz. Inhib. hit(s) with Target = 'Beta-secretase 1' and Ligand = 'BDBM50317053'
TargetBeta-secretase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50317053(1-butyl-N-((1S,2S)-3-(3,5-difluorophenyl)-1-hydrox...)
Affinity DataKi:  14nMAssay Description:Inhibition oh BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50317053(1-butyl-N-((1S,2S)-3-(3,5-difluorophenyl)-1-hydrox...)
Affinity DataIC50:  1.35E+3nMAssay Description:Inhibition of BACE1 expressed in HEK293 cells expressing human APP assessed as amyloid beta42 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed