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Found 2 Enz. Inhib. hit(s) with Target = 'Beta-secretase 1' and Ligand = 'BDBM50318131'
TargetBeta-secretase 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50318131((14S)-16-amino-10,14-dicyclohexyl-20-fluoro-2-oxa-...)
Affinity DataKi:  8nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50318131((14S)-16-amino-10,14-dicyclohexyl-20-fluoro-2-oxa-...)
Affinity DataIC50:  30nMAssay Description:Inhibition of BACE1 assessed as amyloid beta (1-40) productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed