Compile Data Set for Download or QSAR
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Found 3 Enz. Inhib. hit(s) with Target = 'Beta-secretase 2' and Ligand = 'BDBM26510'
TargetBeta-secretase 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM26510(BMCL193669 Compound 18 | N-[(2S,3R)-4-(cyclopropyl...)
Affinity DataIC50:  263nMpH: 4.5 T: 2°CAssay Description:Enzyme activity and inhibition were assayed using a fluorescent FAM-[SEVNLDAEFK]-TAMRA substrate. Control reactions with no enzyme were included in e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM26510(BMCL193669 Compound 18 | N-[(2S,3R)-4-(cyclopropyl...)
Affinity DataIC50:  263nMAssay Description:Enzyme activity and inhibition were assayed using a fluorescent FAM-[SEVNLDAEFK]-TAMRA substrate. Control reactions with no enzyme were included in e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM26510(BMCL193669 Compound 18 | N-[(2S,3R)-4-(cyclopropyl...)
Affinity DataIC50:  263nMAssay Description:Enzyme activity and inhibition were assayed using a fluorescent FAM-[SEVNLDAEFK]-TAMRA substrate. Control reactions with no enzyme were included in e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed