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Found 2 Enz. Inhib. hit(s) with Target = 'Beta-secretase 2' and Ligand = 'BDBM448222'
TargetBeta-secretase 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM448222(US10689401, EX 24 | US11008338, Example 24)
Affinity DataKi:  109nMAssay Description:BACE2: Inhibitor IC50s at purified human autoBACE-2 are determined in a time-resolved endpoint proteolysis assay that measures hydrolysis of the QSY7...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-secretase 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM448222(US10689401, EX 24 | US11008338, Example 24)
Affinity DataKi:  109nMAssay Description:BACE-2: Inhibitor IC50s at purified human autoBACE-2 are determined in a time-resolved endpoint proteolysis assay that measures hydrolysis of the QSY...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent