Compile Data Set for Download or QSAR
maximum 50k data
Found 4 Enz. Inhib. hit(s) with Target = 'Bile acid receptor' and Ligand = 'BDBM322134'
TargetBile acid receptor(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM322134(8-((5-cyclopropyl-3-(2,6-dichlorophenyl)isoxazol-4...)
Affinity DataEC50:  18nMAssay Description:Purchasing invitrogen PV4833 kits.First, the required amount of the compound was weighed and dissolved in 100% DMSO at the maximum concentration of 3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM322134(8-((5-cyclopropyl-3-(2,6-dichlorophenyl)isoxazol-4...)
Affinity DataEC50:  833nMAssay Description:Agonist activity at FXR-LBD (unknown origin) assessed as induction of coactivator SRC-1 peptide recruitment measured by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBile acid receptor(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM322134(8-((5-cyclopropyl-3-(2,6-dichlorophenyl)isoxazol-4...)
Affinity DataEC50:  345nMAssay Description:Agonist activity at human FXR expressed in HEK293T cells by luciferase reporter assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBile acid receptor(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM322134(8-((5-cyclopropyl-3-(2,6-dichlorophenyl)isoxazol-4...)
Affinity DataEC50:  4nMAssay Description:Purchasing invitrogen PV4833 kits.First, the required amount of the compound was weighed and dissolved in 100% DMSO at the maximum concentration of 3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent