BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'C5a anaphylatoxin chemotactic receptor' and Ligand = 'BDBM50229910'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
C5a anaphylatoxin chemotactic receptor


(Homo sapiens (Human))
BDBM50229910
PNG
(CHEMBL263759)
Show SMILES Cc1cc(NCc2ccccc2)c2cc(NC(=O)C(=O)Nc3ccc4nc(C)cc(NCc5ccccc5)c4c3)ccc2n1
Show InChI InChI=1S/C36H32N6O2/c1-23-17-33(37-21-25-9-5-3-6-10-25)29-19-27(13-15-31(29)39-23)41-35(43)36(44)42-28-14-16-32-30(20-28)34(18-24(2)40-32)38-22-26-11-7-4-8-12-26/h3-20H,21-22H2,1-2H3,(H,37,39)(H,38,40)(H,41,43)(H,42,44)
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>50n/an/an/an/an/an/a



Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Ability to inhibit binding of radiolabeled C5a anaphylatoxin to intact membrane bound receptor from human neutrophils.


J Med Chem 35: 252-8 (1992)


Article DOI: 10.1021/jm00080a008
More data for this
Ligand-Target Pair