Compile Data Set for Download or QSAR
maximum 50k data
Found 3 Enz. Inhib. hit(s) with Target = 'Calcitonin gene-related peptide type 1 receptor' and Ligand = 'BDBM50173468'
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50173468(4-(2-Oxo-1,4-dihydro-2H-quinazolin-3-yl)-piperidin...)
Affinity DataIC50:  0.0300nMpH: 7.4Assay Description:Affinity against human calcitonin gene related peptide receptor (1 uM) expressed in SK-N-MC cells using [125I]-CGRP as radioligand after 180 minutes ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50173468(4-(2-Oxo-1,4-dihydro-2H-quinazolin-3-yl)-piperidin...)
Affinity DataIC50:  0.0600nMpH: 7.4Assay Description:Affinity against calcitonin gene related peptide receptor (1 uM) in marmoset tissue homogenates using [125I]-CGRP as radioligand after 180 minutes of...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Rattus norvegicus)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50173468(4-(2-Oxo-1,4-dihydro-2H-quinazolin-3-yl)-piperidin...)
Affinity DataIC50:  6.40nMpH: 7.4Assay Description:Affinity against calcitonin gene related peptide receptor (1 uM) in rat spleen using [125I]-CGRP as radioligand after 180 minutes of incubation at pH...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed