Compile Data Set for Download or QSAR
maximum 50k data
Found 3 Enz. Inhib. hit(s) with Target = 'Calcitonin gene-related peptide type 1 receptor' and Ligand = 'BDBM50315400'
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50315400((S)-1-((3'-methyl-2',5'-dioxo-6,8-dihydrospiro[cyc...)
Affinity DataKi:  0.300nMAssay Description:Displacement of [125I]human CLR from human CGRP expressed in HEK293 cells coexpressing human RAMP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50315400((S)-1-((3'-methyl-2',5'-dioxo-6,8-dihydrospiro[cyc...)
Affinity DataIC50:  1.70nMAssay Description:Antagonist activity at human CLR expressed in human HEK293 cells coexpressing human RAMP1 assessed as Inhibition of CGRP-induced cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50315400((S)-1-((3'-methyl-2',5'-dioxo-6,8-dihydrospiro[cyc...)
Affinity DataIC50:  14nMAssay Description:Antagonist activity at human CLR expressed in human HEK293 cells coexpressing human RAMP1 assessed as Inhibition of CGRP-induced cAMP production in t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed