Found 5 Enz. Inhib. hit(s) with Target = 'Calcium-dependent protein kinase 1' and Ligand = 'BDBM36336' TargetCalcium-dependent protein kinase 1(Plasmodium Falciparum)
University Of North Carolina At Chapel Hill
Curated by ChEMBL
University Of North Carolina At Chapel Hill
Curated by ChEMBL
Affinity DataIC50: 2.10nMAssay Description:Inhibition of Plasmodium falciparum CDPK1 measured after 2 hrs by luciferin based luminescence assayMore data for this Ligand-Target Pair
TargetCalcium-dependent protein kinase 1(Plasmodium Falciparum)
University Of North Carolina At Chapel Hill
Curated by ChEMBL
University Of North Carolina At Chapel Hill
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of Plasmodium falciparum recombinant CDPK1 expressed in Escherichia coli expression system after 1 hr in presence of [gamma33P]ATP by scin...More data for this Ligand-Target Pair
TargetCalcium-dependent protein kinase 1(Plasmodium Falciparum)
University Of North Carolina At Chapel Hill
Curated by ChEMBL
University Of North Carolina At Chapel Hill
Curated by ChEMBL
Affinity DataIC50: 17nMpH: 7.5 T: 2°CAssay Description:The test compounds and enzyme were mixed in buffer, and the substrate and [gamma-33P] ATP/ATP were added to the mixture to initiate the reaction. Aft...More data for this Ligand-Target Pair
TargetCalcium-dependent protein kinase 1(Plasmodium Falciparum)
University Of North Carolina At Chapel Hill
Curated by ChEMBL
University Of North Carolina At Chapel Hill
Curated by ChEMBL
Affinity DataEC50: 230nMpH: 7.5 T: 2°CAssay Description:This parasite proliferation assay, a modification of published DNA intercalating fluorescent dye-based assay, was adapted to 384-well plate format an...More data for this Ligand-Target Pair
TargetCalcium-dependent protein kinase 1(Plasmodium Falciparum)
University Of North Carolina At Chapel Hill
Curated by ChEMBL
University Of North Carolina At Chapel Hill
Curated by ChEMBL
Affinity DataEC50: 230nMpH: 7.5 T: 2°CAssay Description:This parasite proliferation assay, a modification of published DNA intercalating fluorescent dye-based assay, was adapted to 384-well plate format an...More data for this Ligand-Target Pair
