Found 31 Enz. Inhib. hit(s) with Target = 'Carbonic anhydrase 1' and Ligand = 'BDBM10888' 
Affinity DataKi: 56nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Affinity DataKi: 56nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Affinity DataKi: 56nMAssay Description:Inhibition of human recombinant full length CA1-mediated CO2 hydration preincubated for 15 mins by stopped-flow assayMore data for this Ligand-Target Pair
Affinity DataKi: 56nMAssay Description:Inhibition of human recombinant CA1 by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 56nMAssay Description:Inhibition of human cloned CA1 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 56nMAssay Description:Inhibition of human recombinant cytosolic carbonic anhydrase 1 pre-incubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 56nMAssay Description:Inhibition of human recombinant CA1 by stopped-flow CO2 assayMore data for this Ligand-Target Pair
Affinity DataKi: 56nM ΔG°: -40.7kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
Affinity DataKi: 56nMAssay Description:Inhibition of human recombinant carbonic anhydrase 1 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
Affinity DataKi: 56nMAssay Description:Inhibition of human carbonic anhydrase-1 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 56nMAssay Description:Inhibition of wild type human recombinant carbonic anhydrase 1 expressed in Escherichia coli BL21 (DE3) after 15 mins by CO2 hydration methodMore data for this Ligand-Target Pair
Affinity DataKi: 56nMAssay Description:Inhibition of human recombinant CA1 by stopped-flow CO2 hydration assayChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 56nMpH: 7.5Assay Description:Inhibition of human carbonic anhydrase 1 after 15 mins by CO2 hydrase assay at pH 7.5More data for this Ligand-Target Pair
Affinity DataKi: 56nMAssay Description:Inhibition of human recombinant CA1 cytosolic isoform by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 56nMAssay Description:Inhibition of human recombinant alpha-carbonic anhydrase 1 after 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 56nMpH: 7.5Assay Description:Inhibition of human carbonic anhydrase I by spectrophotometry at pH 7.5More data for this Ligand-Target Pair
Affinity DataKi: 56nMAssay Description:Inhibition of human carbonic anhydrase 1 preincubated with compound for 15 mins by carbon dioxide hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 56nMAssay Description:Inhibition of human recombinant carbonic anhydrase 1 by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
Affinity DataKi: 56nMpH: 7.5Assay Description:Inhibition of human recombinant carbonic anhydrase 1 at pH 7.5 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 56nMAssay Description:Inhibition of human recombinant full length CA1 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 56nMAssay Description:Inhibition of human recombinant carbonic anhydrase 1 after 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 56nMAssay Description:Inhibition of human recombinant CA1More data for this Ligand-Target Pair
Affinity DataKi: 56nMAssay Description:Inhibition of human recombinant carbonic anhydrase 1 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 56nMAssay Description:Inhibition of human recombinant CA1 by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 56nMAssay Description:Inhibition of human cloned CA1 by CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 60nM ΔG°: -41.2kJ/molepH: 7.5 T: 2°CAssay Description:Phenol red (at a concentration of 0.2 mM) has been used as indicator, working at the absorbance maximum of 557 nm, with 10 mM Tris-HCl (pH 7.5) as bu...More data for this Ligand-Target Pair
Affinity DataKi: 1.48E+4nMAssay Description:Inhibition of human carbonic anhydrase 1 esterase activity using 4-nitrophenylacetate as substrateMore data for this Ligand-Target Pair
Affinity DataKi: 1.48E+4nMpH: 7.4Assay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
Affinity DataKi: 1.48E+4nMAssay Description:Kinetic studies were performed using the esterase activity method, with 4-nitrophenyl acetate (NPA) as substrate.More data for this Ligand-Target Pair
Affinity DataKi: 1.48E+4nMAssay Description:Inhibition of human carbonic anhydrase 1 using 4-nitrophenylacetate as substrate after 3 mins using spectrophotometry by Lineweaver-Burk plot analysi...More data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:Compounds which are CAIs are well known in the art, see for example, Pastorekova et al, Journal of Enzyme Inhibition and Medicinal Chemistry, 19(3), ...More data for this Ligand-Target Pair
