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Found 2 Enz. Inhib. hit(s) with Target = 'Carbonic anhydrase 2' and Ligand = 'BDBM11417'
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Alcon Research

LigandPNGBDBM11417(2H-Thieno[3,2-e]-1,2-thiazine-6-sulfonamide 1,1-di...)
Affinity DataKi:  0.260nMAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Alcon Research

LigandPNGBDBM11417(2H-Thieno[3,2-e]-1,2-thiazine-6-sulfonamide 1,1-di...)
Affinity DataIC50:  3.12nMAssay Description:The assay measured the rate of CO2 hydration by determining the addition rate of a NaOH solution using a Radiometer VIT 90 titration system. The enzy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed