Compile Data Set for Download or QSAR
Found 5 Enz. Inhib. hit(s) with Target = 'Carbonic anhydrase 2' and Ligand = 'BDBM50101343'
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universit£ degli Studi

Curated by ChEMBL
LigandPNGBDBM50101343((4-Sulfamoyl-benzoylamino)-acetic acid | CHEMBL513...)
Show SMILES NS(=O)(=O)c1ccc(cc1)C(=O)NCC(O)=O
Show InChI InChI=1S/C9H10N2O5S/c10-17(15,16)7-3-1-6(2-4-7)9(14)11-5-8(12)13/h1-4H,5H2,(H,11,14)(H,12,13)(H2,10,15,16)
Affinity DataKi:  85nMAssay Description:Binding affinity against human carbonic anhydrase II (hCA -II)More data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universit£ degli Studi

Curated by ChEMBL
LigandPNGBDBM50101343((4-Sulfamoyl-benzoylamino)-acetic acid | CHEMBL513...)
Show SMILES NS(=O)(=O)c1ccc(cc1)C(=O)NCC(O)=O
Show InChI InChI=1S/C9H10N2O5S/c10-17(15,16)7-3-1-6(2-4-7)9(14)11-5-8(12)13/h1-4H,5H2,(H,11,14)(H,12,13)(H2,10,15,16)
Affinity DataKd:  330nMAssay Description:Dissociation constant was determined against human carbonic anhydrase II at 37 degree Centigrade in experiment 2More data for this Ligand-Target Pair
In DepthDetails Article
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universit£ degli Studi

Curated by ChEMBL
LigandPNGBDBM50101343((4-Sulfamoyl-benzoylamino)-acetic acid | CHEMBL513...)
Show SMILES NS(=O)(=O)c1ccc(cc1)C(=O)NCC(O)=O
Show InChI InChI=1S/C9H10N2O5S/c10-17(15,16)7-3-1-6(2-4-7)9(14)11-5-8(12)13/h1-4H,5H2,(H,11,14)(H,12,13)(H2,10,15,16)
Affinity DataKd:  310nMAssay Description:Kinetic constant for binding human carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universit£ degli Studi

Curated by ChEMBL
LigandPNGBDBM50101343((4-Sulfamoyl-benzoylamino)-acetic acid | CHEMBL513...)
Show SMILES NS(=O)(=O)c1ccc(cc1)C(=O)NCC(O)=O
Show InChI InChI=1S/C9H10N2O5S/c10-17(15,16)7-3-1-6(2-4-7)9(14)11-5-8(12)13/h1-4H,5H2,(H,11,14)(H,12,13)(H2,10,15,16)
Affinity DataKoff:  3.61E+7s-1Assay Description:Kinetic constant for binding human carbonic anhydrase II (Kon=Kd x Koff)More data for this Ligand-Target Pair
In DepthDetails Article
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universit£ degli Studi

Curated by ChEMBL
LigandPNGBDBM50101343((4-Sulfamoyl-benzoylamino)-acetic acid | CHEMBL513...)
Show SMILES NS(=O)(=O)c1ccc(cc1)C(=O)NCC(O)=O
Show InChI InChI=1S/C9H10N2O5S/c10-17(15,16)7-3-1-6(2-4-7)9(14)11-5-8(12)13/h1-4H,5H2,(H,11,14)(H,12,13)(H2,10,15,16)
Affinity DataKon:  0.120M-1s-1Assay Description:Dissociation constant against human carbonic anhydrase II at 37 degree centigradeMore data for this Ligand-Target Pair
In DepthDetails Article