Found 10 Enz. Inhib. hit(s) with Target = 'Caspase-1' and Ligand = 'BDBM10355' 
Affinity DataKi: 0.700nMAssay Description:Inhibition of human ICEMore data for this Ligand-Target Pair
Affinity DataKi: 0.760nMAssay Description:The compound was tested for inhibition of IL-1 beta converting enzyme in whole human blood.More data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:Binding affinity towards IL-1 beta converting enzyme (ICE)More data for this Ligand-Target Pair
Affinity DataIC50: 8.10nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
Affinity DataIC50: 8.40nMpH: 7.4 T: 2°CAssay Description:The caspase enzymatic activity was determined by measuring the accumulation of a fluorogenic product. All assays were prepared in 96-well format. Rec...More data for this Ligand-Target Pair
Affinity DataIC50: 8.40nMAssay Description:Inhibition of caspase 1 by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibition of human ICEMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Ability to inhibit IL-1 beta converting enzyme was evaluated in LPS-stimulated human whole bloodChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 6.80E+4nMAssay Description:Amidolytic activity of THP.1 cell lysate against IL-1 beta converting enzyme using C1-Asp-AMC as a substrateChecked by AuthorMore data for this Ligand-Target Pair
