BindingDB PrimarySearch

Found 2 Enz. Inhib. hit(s) with Target = 'Cathepsin B' and Ligand = 'BDBM16503'

Cathepsin B(Homo sapiens (Human))
TBA

Curated by ChEMBL

BDBM16503(CA inhibitor 6 | CA074Me | PrNH-tES-Ile-Pro-OMe | ...)

IC50: 80nMAssay Description:Inhibition of cathepsin-B using Z-Arg-Arg AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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Details Article PubMed DrugBank
PDB

3D Structure (crystal)

Cathepsin B(Bos taurus (bovine))
Osaka University Of Pharmaceutical Sciences

BDBM16503(CA inhibitor 6 | CA074Me | PrNH-tES-Ile-Pro-OMe | ...)

IC50: 6.80E+4nMpH: 6.0 T: 2°CAssay Description:Inhibitory activities (IC50, concentration of 50% inhibition) of compounds for bovine CB in vitro were determined by monitoring the cleavage of fluor...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Purchase DrugBank KEGG PC cid PC sid PDB Similars

Details Article PubMed PDB

3D Structure (crystal)