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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Chymase' and Ligand = 'BDBM50098841'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Chymase


(Homo sapiens (Human))
BDBM50098841
PNG
(2-(2-{2-[5-Amino-2-(3-amino-phenyl)-6-oxo-6H-pyrim...)
Show SMILES COC(=O)c1ccc2oc(nc2c1)C(=O)C(Cc1ccccc1)NC(=O)Cn1c(ncc(N)c1=O)-c1cccc(N)c1
Show InChI InChI=1/C30H26N6O6/c1-41-30(40)19-10-11-24-22(14-19)35-28(42-24)26(38)23(12-17-6-3-2-4-7-17)34-25(37)16-36-27(33-15-21(32)29(36)39)18-8-5-9-20(31)13-18/h2-11,13-15,23H,12,16,31-32H2,1H3,(H,34,37)
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Similars

Article
PubMed
5.60n/an/an/an/an/an/an/an/a



Welfide Corporation

Curated by ChEMBL


Assay Description
Inhibitory activity evaluated against chymase from human heart.


J Med Chem 44: 1286-96 (2001)


Article DOI: 10.1021/jm000496v
BindingDB Entry DOI: 10.7270/Q26H4J4K
More data for this
Ligand-Target Pair