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Found 1 Enz. Inhib. hit(s) with Target = 'Coagulation factor XII' and Ligand = 'BDBM498915'
TargetCoagulation factor XII(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM498915(N-{(3S,4R)-1-[N~2~- cyclohexyl-N~6~- (methylsulfon...)
Affinity DataIC50:  52.4nMAssay Description:Factor XIIa activity determinations were made in 50 mM HEPES buffer containing 150 mM NaCl, 5 mM CaCl2, and 0.1% PEG 8000 (polyethylene glycol; JT Ba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent