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Found 8 Enz. Inhib. hit(s) with Target = 'D(3) dopamine receptor' and Ligand = 'BDBM50161214'
TargetD(3) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50161214(CHEMBL180010 | N-(4-(4-(2,3-dichlorophenyl)piperaz...)
Affinity DataKi:  0.316nMAssay Description:Displacement of [3H]N-methylspiperone from human dopamine D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50161214(CHEMBL180010 | N-(4-(4-(2,3-dichlorophenyl)piperaz...)
Affinity DataKi:  0.700nMAssay Description:Binding affinity for human dopamine D3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50161214(CHEMBL180010 | N-(4-(4-(2,3-dichlorophenyl)piperaz...)
Affinity DataKi:  0.700nMAssay Description:Displacement of [125I]IABN from human dopamine D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50161214(CHEMBL180010 | N-(4-(4-(2,3-dichlorophenyl)piperaz...)
Affinity DataKi:  0.700nMAssay Description:Displacement of [125I]-IABN from human dopamine D3 receptor expressed in HEK293 cells after 60 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50161214(CHEMBL180010 | N-(4-(4-(2,3-dichlorophenyl)piperaz...)
Affinity DataKi:  0.700nMAssay Description:Inhibition of [125I]IABN binding to human Dopamine D3 receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50161214(CHEMBL180010 | N-(4-(4-(2,3-dichlorophenyl)piperaz...)
Affinity DataKi:  2.11nMAssay Description:Inhibition of [3H]YM-09151-2 binding to human Dopamine D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50161214(CHEMBL180010 | N-(4-(4-(2,3-dichlorophenyl)piperaz...)
Affinity DataIC50:  3nMAssay Description:Antagonist activity at human dopamine D3 receptor expressed in HEK293 cells by mitogenesis assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50161214(CHEMBL180010 | N-(4-(4-(2,3-dichlorophenyl)piperaz...)
Affinity DataIC50:  3.01nMAssay Description:Mitogenic stimulation or antagonism of 30 nM quinpirole-stimulated mitogenesis in CHO cells expressing human dopamine D3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed