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Found 7 Enz. Inhib. hit(s) with Target = 'D-amino-acid oxidase' and Ligand = 'BDBM50433372'
TargetD-amino-acid oxidase(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50433372(CHEMBL2375520)
Affinity DataKi:  1.70nMAssay Description:Competitive inhibition of human recombinant DAAO by Michaelis-Menten plot analysis in presence of D-serineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50433372(CHEMBL2375520)
Affinity DataIC50:  3.10nMAssay Description:Competitive inhibition of human recombinant DAAO after 1 hr by coupled enzyme assay in presence of D-serineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50433372(CHEMBL2375520)
Affinity DataKd:  4.00E+3nMAssay Description:Binding affinity to human recombinant DAAO at 395 nm spectral modification by spectrophotometric analysis in presence of FADMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50433372(CHEMBL2375520)
Affinity DataKd:  4.20E+3nMAssay Description:Binding affinity to human recombinant DAAO at 444 nm spectral modification by spectrophotometric analysis in presence of FADMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50433372(CHEMBL2375520)
Affinity DataKd:  4.20E+3nMAssay Description:Binding affinity to human recombinant DAAO at 498 nm spectral modification by spectrophotometric analysis in presence of FADMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50433372(CHEMBL2375520)
Affinity DataKd:  1.90E+3nMAssay Description:Binding affinity to human recombinant DAAO by stopped flow spectrophotometric analysis in presence of FADMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50433372(CHEMBL2375520)
Affinity DataKd:  3.60E+3nMAssay Description:Binding affinity to human recombinant DAAO at 362 nm spectral modification by spectrophotometric analysis in presence of FADMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed