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Compile Data Set for Download or QSAR

Found 12 hits Enz. Inhib. hit(s) with Target = 'DOPAMINE' and Ligand = 'BDBM55121'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
DOPAMINE


(RAT)
BDBM55121
PNG
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Show SMILES NCCc1ccc(O)c(O)c1
Show InChI InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2
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150n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Displacement of [3H]fenoldopam from Dopamine receptor D1 of rat striatum membranes


J Med Chem 29: 1904-12 (1986)


Article DOI: 10.1021/jm00160a018
BindingDB Entry DOI: 10.7270/Q2TQ623R
More data for this
Ligand-Target Pair
DOPAMINE


(RAT)
BDBM55121
PNG
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Show SMILES NCCc1ccc(O)c(O)c1
Show InChI InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2
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220n/an/an/an/an/an/an/an/a



Purdue University

Curated by PDSP Ki Database




Bioorg Med Chem 11: 1451-64 (2003)


Article DOI: 10.1016/S0968-0896(02)00561-8
BindingDB Entry DOI: 10.7270/Q2CV4G90
More data for this
Ligand-Target Pair
DOPAMINE


(RAT)
BDBM55121
PNG
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Show SMILES NCCc1ccc(O)c(O)c1
Show InChI InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2
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380n/an/an/an/an/an/an/an/a



Université Catholique de Louvain

Curated by PDSP Ki Database




Life Sci 37: 1971-83 (1985)


BindingDB Entry DOI: 10.7270/Q2HX1B5B
More data for this
Ligand-Target Pair
DOPAMINE


(RAT)
BDBM55121
PNG
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Show SMILES NCCc1ccc(O)c(O)c1
Show InChI InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2
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1.00E+3n/an/an/an/an/an/an/an/a



Purdue University

Curated by PDSP Ki Database




Bioorg Med Chem 11: 1451-64 (2003)


Article DOI: 10.1016/S0968-0896(02)00561-8
BindingDB Entry DOI: 10.7270/Q2CV4G90
More data for this
Ligand-Target Pair
DOPAMINE


(RAT)
BDBM55121
PNG
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Show SMILES NCCc1ccc(O)c(O)c1
Show InChI InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2
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>1.00E+3n/an/an/an/an/an/an/an/a



Universit£ di Camerino

Curated by ChEMBL


Assay Description
Binding affinity at Dopamine receptor D1 in rat neostriatum by [3H]-SCH- 23390 displacement.


J Med Chem 39: 4238-46 (1996)


Article DOI: 10.1021/jm960318v
BindingDB Entry DOI: 10.7270/Q2WQ04FD
More data for this
Ligand-Target Pair
DOPAMINE


(RAT)
BDBM55121
PNG
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Show SMILES NCCc1ccc(O)c(O)c1
Show InChI InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2
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1.45E+3n/an/an/an/an/an/an/an/a



Schering-Plough Corporation

Curated by PDSP Ki Database




Life Sci 35: 1885-93 (1984)


BindingDB Entry DOI: 10.7270/Q2JD4V9M
More data for this
Ligand-Target Pair
DOPAMINE


(RAT)
BDBM55121
PNG
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Show SMILES NCCc1ccc(O)c(O)c1
Show InChI InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2
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4.40E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro affinity against Dopamine receptor D1 using [3H]SCH-23390 radioligand in rat striatal homogenate.


J Med Chem 29: 1889-95 (1986)


Article DOI: 10.1021/jm00160a016
BindingDB Entry DOI: 10.7270/Q2ZC83F6
More data for this
Ligand-Target Pair
DOPAMINE


(RAT)
BDBM55121
PNG
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Show SMILES NCCc1ccc(O)c(O)c1
Show InChI InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2
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n/an/a 800n/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Displacement of [3H]- #NAME? from binding Dopamine receptor D1 in rat striatum


J Med Chem 33: 1756-64 (1990)


Article DOI: 10.1021/jm00168a034
BindingDB Entry DOI: 10.7270/Q23X877X
More data for this
Ligand-Target Pair
DOPAMINE


(RAT)
BDBM55121
PNG
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Show SMILES NCCc1ccc(O)c(O)c1
Show InChI InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2
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n/an/a 3.00E+3n/an/an/an/an/an/a



University of Camerino

Curated by ChEMBL


Assay Description
Compound was evaluated for the inhibition of [3H]-SCH- 23390 binding to Dopamine receptor D1 of rat striatal membranes


J Med Chem 33: 2408-12 (1990)


Article DOI: 10.1021/jm00171a014
BindingDB Entry DOI: 10.7270/Q29G5NFT
More data for this
Ligand-Target Pair
DOPAMINE


(RAT)
BDBM55121
PNG
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Show SMILES NCCc1ccc(O)c(O)c1
Show InChI InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2
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n/an/a 3.70E+3n/an/an/an/an/an/a



University of Camerino

Curated by ChEMBL


Assay Description
Inhibitory activity against [3H]-SCH- 23390 in Rat Striatal membrane


J Med Chem 35: 4408-14 (1992)


Article DOI: 10.1021/jm00101a018
BindingDB Entry DOI: 10.7270/Q2WH2QMC
More data for this
Ligand-Target Pair
DOPAMINE


(RAT)
BDBM55121
PNG
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Show SMILES NCCc1ccc(O)c(O)c1
Show InChI InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2
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n/an/an/an/a 3.50E+3n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Dopamine receptor D1 agonist efficacy was measured with stimulation of dopamine-sensitive rat adenylate cyclase in caudate membranes


J Med Chem 30: 1166-76 (1987)


Article DOI: 10.1021/jm00390a009
BindingDB Entry DOI: 10.7270/Q2028QJ6
More data for this
Ligand-Target Pair
DOPAMINE


(RAT)
BDBM55121
PNG
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Show SMILES NCCc1ccc(O)c(O)c1
Show InChI InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2
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n/an/an/an/a 5.00E+3n/an/an/an/a



University of North Carolina

Curated by ChEMBL


Assay Description
Effective concentration was determined for the adenylate cyclase activity in rat striatal tissue as a measure of Dopamine receptor D1 functional acti...


J Med Chem 39: 285-96 (1996)


Article DOI: 10.1021/jm9502100
BindingDB Entry DOI: 10.7270/Q2NZ86Q3
More data for this
Ligand-Target Pair