BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Diacylglycerol O-acyltransferase 1 (DGAT1)' and Ligand = 'BDBM220395'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Diacylglycerol O-acyltransferase 1 (DGAT1)


(Homo sapiens (Human))
BDBM220395
PNG
(US9296708, 1, ARM-P0)
Show SMILES OC(=O)CC[C@H](NC(=O)N[C@@H](CCCCn1cc(CNc2ccc(cc2[N+]([O-])=O)[N+]([O-])=O)nn1)C(O)=O)C(O)=O
Show InChI InChI=1S/C21H26N8O11/c30-18(31)7-6-16(20(34)35)24-21(36)23-15(19(32)33)3-1-2-8-27-11-12(25-26-27)10-22-14-5-4-13(28(37)38)9-17(14)29(39)40/h4-5,9,11,15-16,22H,1-3,6-8,10H2,(H,30,31)(H,32,33)(H,34,35)(H2,23,24,36)/t15-,16-/m0/s1
UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
0.0780n/a 1.76n/an/an/an/an/an/a



YALE UNIVERSITY

US Patent


Assay Description
For IC50 measurements, inhibitors were dissolved in Reaction Buffer containing 40 μM NAAG to a final volume of 100 μL. Then, 25 μL of this s...


US Patent US9296708 (2016)


BindingDB Entry DOI: 10.7270/Q2BP01P0
More data for this
Ligand-Target Pair