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Found 2 Enz. Inhib. hit(s) with Target = 'Diacylglycerol O-acyltransferase 2' and Ligand = 'BDBM503720'
TargetDiacylglycerol O-acyltransferase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM503720(US11034678, Example 3.6)
Affinity DataIC50:  35nMAssay Description:Inhibition of human DGAT2 expressed in Sf9 insect cell membrane using [1-14C]decanoyl-CoA and 1,2-didecanoyl-sn-glycerol as substrates assessed as in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetDiacylglycerol O-acyltransferase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM503720(US11034678, Example 3.6)
Affinity DataIC50:  35.4nMAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 1 &#...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent