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Found 2 Enz. Inhib. hit(s) with Target = 'Diacylglycerol O-acyltransferase 2' and Ligand = 'BDBM530621'
TargetDiacylglycerol O-acyltransferase 2(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM530621(1-(5-(difluoromethoxy)-2-fluorophenyl)-3-(3-hydrox...)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of human DGAT2 expressed in sf9 insect cell membrane assessed as reduction in 13C18-triolein product formation using 13C oleoyl-CoA as sub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetDiacylglycerol O-acyltransferase 2(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM530621(1-(5-(difluoromethoxy)-2-fluorophenyl)-3-(3-hydrox...)
Affinity DataIC50:  0.700nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed