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Found 4 Enz. Inhib. hit(s) with Target = 'Dihydrofolate reductase' and Ligand = 'BDBM50081921'
TargetDihydrofolate reductase(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50081921(5-(4-Ethoxy-benzyl)-pyrimidine-2,4-diamine | CHEMB...)
Affinity DataKi:  9.80nMAssay Description:Inhibition of recombinant Dihydrofolate reductase from humans.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50081921(5-(4-Ethoxy-benzyl)-pyrimidine-2,4-diamine | CHEMB...)
Affinity DataKi:  130nMAssay Description:Inhibition of recombinant Dihydrofolate reductase from Leishmania major.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50081921(5-(4-Ethoxy-benzyl)-pyrimidine-2,4-diamine | CHEMB...)
Affinity DataKi:  210nMAssay Description:Inhibition of recombinant Dihydrofolate reductase from Trypanosoma cruzi.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50081921(5-(4-Ethoxy-benzyl)-pyrimidine-2,4-diamine | CHEMB...)
Affinity DataKi:  6.00E+3nMAssay Description:Inhibition of recombinant Dihydrofolate reductase from humans.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed